Chromatographic capacity factor

Hafkenscheid, T.L., Tomlinson, E. (1983) Correlations between alkane/water and octan-l-ol/water distribution coefficients and isocratic reversed-phase liquid chromatographic capacity factors of acids, bases and neutrals. Int l. J. Pharmaceu. 16, 225-239. 

The chromatographic capacity factor (AT ) for ester and amide derivatives of 6,6a, 7,8,9,10,10a, 11-octahydro-ll-oxodibenzo[ /]thiepine propionic acid 44, potent antiinflammatory agents, has been studied, since the parameter was widely used for the interpretation of the activity of drugs <2003RRC795>. K, was modeled topologically using molecular redundancy index (MRI), equalized electronegativity (xeq), and van der Waals volume (fw)-... 

M. H. Abraham and M. Roses, Hydrogen bonding. 38. Effect of solute structure and mobile phase composition on reversed-phase high-performance liquid chromatographic capacity factors, J. Phys. Org. Chem. 7 (1994), 672-683. 

Hammers, W.E., Meurs, G.J., DeLigny, C.L. (1982) Correlations between hquid chromatographic capacity factors ratio data on Lichrosorb RP-18 and partition coefficients in the octanol-water system. J. Chromatogr. 247, 1-13. 

Martorell, C. Calpena, A.C. Escribano, E. Poblet, J.M. Freixas, J. Influence of the chromatographic capacity factor (log L) as an index of lipophilicity in the antibacterial activity of a series of 6-fluoroquinolones. Relationship between physico-chemical and structural properties and their hydrophobicity. J. Chromatogr., A 1993, 655, 177-184. 

This calculation shows how resolution might be obtained for a three component mixture, where two components have the same liquid chromatographic capacity factors (k, = 0.5, i = 2,3) with slightly different electrophoretic fluxes (tuE = -2.7 h2e = -2.2). 

FIGURE 29.1 Relative amount of ethanol produced versus amount of silane adsorbed on the substrate, calculated from the chromatographic capacity factor k. ... 

Table 4.5 Chromatographic Capacity Factor and the Contribution of k to the Fundamental Resolution Equation...

In Eq. (4.10), a chromatographic capacity factor, k, was defined in terms of the product of a partition constant and a phase ratio denoted by p. For a WCOT, p is related to film thickness, df, and column diameter, dc, according to (51)... 

Yes, Perry has considered the relationship between a solute s specific retention volume, Vg (the net retention volume, V f, per gram of liquid phase) and the column temperature (58). Perry s approach is not seen in most other GC texts, so let us derive it here. Before we present his approach, we need to shore up some fundamentals first. One of the few chromatographic relationships to really commit to memory is the relationship among solute retention volume, Vj, column void volume, Vm, and the solute chromatographic capacity factor, k, according to... 

Hafkenscheid, T.L. and E. Tomlinson. Correlations Between AlkaneAVater and Octan-1-ol/Water Distribution Coefficients and Isocratic Reversed-Phase Liquid Chromatographic Capacity Factors of Acids, Bases and Neutrals, Int. J. Pharm., 16 225-239... 

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