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Incretin Hormones

Antidiabetic Drugs other than Insulin. Table 3 Actions of the incretin hormones GIP (glucose-dependent insulinotropic polypeptide, gastric inhibitory peptide) and GLP-1 (glucagon-like peptide-1)... [Pg.122]

Glucose-dependent-insulinotropic peptide Incretin Hormones... [Pg.524]

Incretin Hormones Appetite Control Insulin Receptor... [Pg.538]

Incretin Hormones. Figure 2 The incretin effect. Patients underwent an oral or equivalent intravenous glucose load so that the glycemic profiles became similar. In such conditions, the data show that the oral glucose load is more potent to stimulate insulin secretion than an equivalent intravenous glucose stimulus. [Pg.624]

Incretin Hormones. Figure 3 Processing of the proglucagon. The proglucagon peptide is synthesized in pancreatic cells and cells from the gastrointestinal (Gl) tract and the brain. Different proconvertases process the peptide so that in the pancreas the glucagon is produced whereas in the Gl tract and the brain, the GLP-1 and GLP-2 peptides are mainly released. [Pg.624]

Schirra J, Katschinski M, Weidmann C, Schafer T, Wank U, Arnold R, Goke B. Gastric emptying and release of incretin hormones after glucose ingestion in humans. J Clin Invest 1996 97(1) 92-103. [Pg.187]

The incretin hormone glucagon-like peptide-1 (GLP-1) plays a crucial role in the regulation of insulin by acting on the pancreas to potentiate glucose-induced insulin secretion. GLP-1 is rapidly cleaved by serine protease dipeptidylpeptidase IV. The inhibitors of DDP-IV are new drugs for the oral treatment of type 2 diabetes. [Pg.332]

Bloomgarden ZT Gut-derived incretin hormones and new therapeutic approaches. Diabetes Care 2004 27 2554. [PMID 15451935]... [Pg.950]

Efendic S, Portwood N. Overview of incretin hormones. Horm Metab Res. 2004 36 742-746. [Pg.493]

The approval of sitagliptin (1) by the U.S. FDA in 2006 established dipeptidyl peptidase IV (DPP-4) inhibitors as an important new therapy for the treatment of type 2 diabetes.4 7 DPP-4 inhibitors stimulate insulin secretion indirectly by enhancing the action of the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (G1P). GLP-1 and G1P stimulate insulin secretion in a... [Pg.125]

Shown to inhibit gut motility and gastrointestinal and pancreatic secretions. It inhibits appetite-stimulating NPY/AgRP-producing neurons (see below), thus signaUing food intake and damping hunger. Many of these gut peptides are incretin hormones, which also stimulate insulin release. [Pg.61]

Glucose-dependent insulinotropic polypeptide (GIP) analogs Incretin hormone analog D-Ala2GIP... [Pg.381]

See other pages where Incretin Hormones is mentioned: [Pg.121]    [Pg.159]    [Pg.213]    [Pg.537]    [Pg.538]    [Pg.623]    [Pg.623]    [Pg.623]    [Pg.624]    [Pg.625]    [Pg.626]    [Pg.935]    [Pg.1494]    [Pg.657]    [Pg.660]    [Pg.97]    [Pg.541]    [Pg.401]    [Pg.343]    [Pg.121]    [Pg.159]    [Pg.213]    [Pg.537]    [Pg.538]    [Pg.623]    [Pg.623]    [Pg.623]    [Pg.624]    [Pg.625]    [Pg.626]    [Pg.935]    [Pg.126]    [Pg.129]   


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