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Jet mixers, impinging

Robustness test for the impinging-jet mixer - fouling sensitivity during precipitations... [Pg.267]

Figure 1.198 Types of flow for different impinging jet mixers, using the acetyl chloride (THF) and n-butylamine/triethylamine (THF) solutions ([53] source IMM). Top left wobbly jet, T-type (initial flow before plugging) total flow rate 200 ml tf1, mixer type 3. Top middle stable jet,... Figure 1.198 Types of flow for different impinging jet mixers, using the acetyl chloride (THF) and n-butylamine/triethylamine (THF) solutions ([53] source IMM). Top left wobbly jet, T-type (initial flow before plugging) total flow rate 200 ml tf1, mixer type 3. Top middle stable jet,...
It turned out that one impinging jet mixer design (two 350 pm openings, separated by 3 mm, and inclined to each other by 45°), giving stable Y-type flows, was particularly advantageous [53],... [Pg.269]

The predictions of the simulations were corroborated by experimental findings. For the liquid-flow splitting unit without an additional micro device as flow resistor, a minimum/maximum flow deviation of about 6% (see Figure 4.101) was found at a low pressure drop below 10 mbar [141]. The maximum flow deviation for the liquid flow-spitting unit equipped with these six selected impinging-jet mixers amounted for initial tests to 11% (4% standard deviation) at 64-74 mbar pressure drop (see Figure 4.101). By optimization of material pretreatment and micro fabrication, a minimum/maximum deviation of the water distribution below 5% and a standard deviation below 2% were finally obtained. [Pg.618]

RAPID MIXING AND RAPID PRECIPITATION WITH AN IMPINGING JET MIXER... [Pg.264]

B.K. Johnson, R.K. Prud homme, Hash NanoPrecipitation of organic actives and block copolymers using a confined impinging jets mixer, Aust. J. Chem. 56 (2003) 1021. [Pg.396]

Keywords Nanocapsules, nanospheres, polymer nanoparticles, confined impinging jets mixer, vortex mixer, flash nanoprecipitation, solvent displacement, freeze-drying, lyoprotectants,... [Pg.229]

Figure 9.1 Example of dependence of characteristic process times ( , nucleation time A, aggregation time , growth time and total mixing time (O) on inlet water jet velocity in a confined impinging jet mixer (ClJ-dl) calculated for PCL (iW = 14,000) nanoparticles formation, polymer initial concentration in acetone = 2.5 mg/mL with water/acetone volumetric flow rate ratio = 2 (redrawn from [42,43])... Figure 9.1 Example of dependence of characteristic process times ( , nucleation time A, aggregation time , growth time and total mixing time (O) on inlet water jet velocity in a confined impinging jet mixer (ClJ-dl) calculated for PCL (iW = 14,000) nanoparticles formation, polymer initial concentration in acetone = 2.5 mg/mL with water/acetone volumetric flow rate ratio = 2 (redrawn from [42,43])...
As the final particle size is influenced by the mixer geometry, other than feed rate, it was also proposed to modulate the particle size varying the mixer geometry, by means of an adjustable confined impinging jets mixer [69]. [Pg.240]

Valente, B. Stella, D.L Marchisio, F. Dosio, and A.A. Barresi, Production of PEGylated nanocapsules through solvent displacement in confined impinging jet mixers. Journal of Pharmaceutical Science, 101 (7), 2490-2501, 2012. [Pg.276]

Valente, E. Celasco, D.L. Marchisio, and A.A. Barresi, Nemoprecipitation in confined impinging jets mixers Production, characterization and scede up of PEGylated nanospheres and nanocapsules for pharmaceutical use. Chemical Engineering Science, 77, 217-227, 2012. [Pg.278]

Tee mixers, impingement jet mixers, and spray nozzles (for liquid into gas) are also often used, especially when adequate pressure energy is available or can be made available in the additive stream. These sidestream additive injection devices are sometimes used in combination with static mixers to optimize design and performance. The design and application of tee mixers are described in detail in the following section. [Pg.397]

Flow Regime Pipe Tee Mixer Impingement Jet Mixer Spray Nozzle Static Mixer Inline Mechanical... [Pg.398]

Figure 17.18 Schematic to illustrate flash nanoprecipitation as a method of nanoparticle formation. (Reproduced with permission from B.K. Johnson and R.K. Prud homme, Flash nanoprecipitation of organic actives and block copolymers using a confined impinging jets mixer, Australian Journal of Chemistry, 56, 10, 1021-1024. CSIRO 2003.) (http //www.publish.csiro.au/paper/CH03115.htm)... Figure 17.18 Schematic to illustrate flash nanoprecipitation as a method of nanoparticle formation. (Reproduced with permission from B.K. Johnson and R.K. Prud homme, Flash nanoprecipitation of organic actives and block copolymers using a confined impinging jets mixer, Australian Journal of Chemistry, 56, 10, 1021-1024. CSIRO 2003.) (http //www.publish.csiro.au/paper/CH03115.htm)...
Fig. 9.12 Different nanoprecipitation devices a bulk dropwise process [74], b pressure driven injection device [74], c confined impinging jet mixer [54], and d continuous flow setup [6]... Fig. 9.12 Different nanoprecipitation devices a bulk dropwise process [74], b pressure driven injection device [74], c confined impinging jet mixer [54], and d continuous flow setup [6]...
Wong I, Ho CM (2009) Surface molecular property modifications for poly (dimethylsiloxane) (PDMS) based microfluidic devices. Microfluid Nanofluid 7(3) 291-306 Valente I, Celasco E, Marchisio DL, Barresi AA (2012) Nanoprecipitation in confined impinging jets mixers production, characterization and scale-up of pegylated nanospheres and nanocapsules for pharmaceutical use. Chem Eng Sci 77 217-227... [Pg.281]

See other pages where Jet mixers, impinging is mentioned: [Pg.107]    [Pg.428]    [Pg.429]    [Pg.266]    [Pg.266]    [Pg.267]    [Pg.268]    [Pg.269]    [Pg.615]    [Pg.217]    [Pg.618]    [Pg.73]    [Pg.569]    [Pg.584]    [Pg.264]    [Pg.37]    [Pg.238]    [Pg.239]    [Pg.239]    [Pg.243]    [Pg.256]    [Pg.276]    [Pg.391]    [Pg.829]   


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