Flash NanoPrecipitation

Johnson, B.J. (2003). Flash nanoprecipitation of organic actives via confined micromixing and block copolymer stabilization. Ph.D. dissertation, Princeton University, Princeton, NJ. 

M. Akbulut, P. Ginart, M.E. Gindy, C. Theriault, K.H. Chin, W. Soboyejo, et ah. Generic method of preparing multifunctional fluorescent nanoparticles using Flash NanoPrecipitation, Adv. Funct. Mater. 19 (2009) 718-725. 

In a work by Chen et al. [186], Brownian dynamics was used to simulate the formatimi of micelles constituted of PS-PEO in water, with the particular aim of investigating the processes involved in flash nanoprecipitation . The effective (coarse-grained) potential was carefully mapped to experimentally determined... 

Keywords Nanocapsules, nanospheres, polymer nanoparticles, confined impinging jets mixer, vortex mixer, flash nanoprecipitation, solvent displacement, freeze-drying, lyoprotectants,... 

In this chapter the flash nanoprecipitation, that is the process of solvent displacement, has been investigated in detail, together with the use of intensive mixers, as it allows continuous production and is easily transferable to industrial manufacturing. 

B.K. Johnson, and R.K. Prud homme, Flash nanoprecipitation of organic actives and block copolymers using a confined impinging jets mixers, Australian Journal of Chemistry, 56 (10), 1021-1024, 2003. 

Z.X. Zhu, Polymer stabilized nanosuspension via flash nanoprecipitation Nanoparticle formation, formulation and stability, Ph.D. Thesis, University of Minnesota, U.S.A., 2010. 

Prud homme, R., Saad, W., and Mayer, L. (2006) Nanoparticle formation by flash nanoprecipitation using block copolymer directed self-assembly. NSTI Nanotech, 2,824. 

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