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Immunoglobulin gene processing

The repair of double-strand breaks is part of the physiologic process of immunoglobulin gene rearrangement. It... [Pg.337]

Kelley, D.E., Wiedemann, L.M., Pittet, A.-C., Strauss, S., Nelson, K.J., Davis, J., Van Ness, B., Perry, R.P. (1985). Nonproductive kappa immunoglobulin genes recombinational abnormalities and other lesions affecting transcription, RNA processing, turnover, and translation. Mol. Cell. Biol. 5,1660-1675. [Pg.78]

Gene rearrangement is a very complex process, and a detailed consideration is beyond the scope of this book. We discuss only the turning on of immunoglobulin gene expression in which DNA rearrangement positions a promoter in the vicinity of a B cell-specific enhancer (Chapter 14). [Pg.357]

Describe the contributions of the number of immunoglobulin genes (the germ-line repertoire), somatic recombination, and somatic mutation in the generation of antibody diversity. Describe the roles of the V, C, D, and J segment genes in these processes. [Pg.587]

See other pages where Immunoglobulin gene processing is mentioned: [Pg.169]    [Pg.134]    [Pg.81]    [Pg.1184]    [Pg.1861]    [Pg.455]    [Pg.32]    [Pg.35]    [Pg.1330]    [Pg.107]    [Pg.489]    [Pg.490]    [Pg.144]    [Pg.36]    [Pg.44]    [Pg.825]    [Pg.825]    [Pg.826]    [Pg.1035]    [Pg.1036]    [Pg.2440]    [Pg.227]    [Pg.157]    [Pg.164]    [Pg.165]    [Pg.166]    [Pg.189]    [Pg.34]    [Pg.53]    [Pg.633]    [Pg.658]    [Pg.1339]    [Pg.948]    [Pg.927]    [Pg.5]    [Pg.856]    [Pg.857]    [Pg.327]    [Pg.167]    [Pg.182]    [Pg.310]    [Pg.310]    [Pg.315]    [Pg.11]    [Pg.27]    [Pg.202]   
See also in sourсe #XX -- [ Pg.1861 ]



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Immunoglobulin processing

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