Brain imaging agents

Image amplification photography, 113 Image dyes, 104 photography stabilization, 112 Imaging agents brain... 

Technetium-99m bicisate is a brain imaging agent that is used for localization of stroke. The lyopbilized kit contains ethyl cysteine dimer as the active ingredient. 

Meltzer, P. C.,Blundell, P., Jones,A. G. etal. A technetium-99m SPECT imaging agent which targets the dopamine transporter in primate brain. J. Med. Chem. 40 1835-1844, 1997. 

The lipophilic complex 99mTc(IV)-L,L-ECD (62) with a deprotonated L,L-ethylcysteine dimer as ligand, is clinically used as a cerebral perfusion imaging agent. It crosses the blood-brain barrier and... 

E.S. Robinson, R.J. Tyacke, L. Finch, G. Willmott, S. Husbands, D.J. Nutt, A.L. Hudson, Pharmacological characterisation of novel 2-adrenoceptor antagonists as potential brain imaging agents. Neuropharmacology 46 (2004) 847-855. 

A medicinal application for a photochromic dye is the use of compounds of the type 379 as near-infrared imaging agents <2005WO16934>. The compounds are used to label amyloid plaques in the brain and aid in the detection of Alzheimer s disease. 

The two naturally occurring isotopes of copper are stable to nuclear decay. Nine synthetic radioisotopes have been reported ( Cu, Cu, Cu, Cu, Cu, Cu, Cu, " Cu, Cu) withhalf-hves of those nuclides ranging from 31 s ( Cu) to 2.58 days ( Cu). One isotope has been used for medical diagnostic purposes see Metal-based Imaging Agents) to scan the brain and to study Wilson s disease. This isotope, Cu, has a half-life of 12.7 h (decay modes at 0.571 MeV,... 

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