Idiopathic intracranial hypertension

Idiopathic intracranial hypertension There have been reports of idiopathic intracranial hypertension. A cardinal sign of idiopathic intracranial hypertension is papilledema early symptoms may include headache (associated with a change in frequency, pattern, severity, or persistence of particular importance are those headaches that are unremitting in nature) and visual disturbances. 

Headache is a common adverse effect of somatropin. It often occurs early in treatment and usually responds to temporary dosage reduction followed by gradual re-esca-lation (1,24). It can be an early indicator of the rare complication pseudotumor cerebri (idiopathic intracranial hypertension), particularly in high-risk groups, such... 

Herrmann KA, Sporer B, Yousry TA (2004) Thrombosis of the internal cerebral vein associated with transient unilateral thalamic edema a case report and review of the literature. AJNR Am J Neuroradiol 25 1351-1355 Higgins JNP, Gillard JH, Owler BK et al (2004) MR venography in idiopathic intracranial hypertension unappreciated and misunderstood. J Neurol Neurosurg Psychiatry 75 621-625... 

Fig. 18.2. a,b Normal venous anomaly in a 3D phase contrast venous angiogram performed at 1.5 T. c,d 3D phase contrast venous angiogram in a patient with idiopathic intracranial hypertension displayed in different projections. The bilateral short stenoses (arrows) are well shown by MR venography, e digital subtraction angiogram in an oblique projection. Confirmation of the obstructed vessel lumen on both sides (arrows), but the finding at this location can only be demonstrated on special projections... 

In patients with idiopathic intracranial hypertension bilaterally narrowed segments in the lateral venous sinuses have been demonstrated compared to normal findings in asymptomatic volunteers using advanced techniques of MR... 

Farb RI, Vanek I, Scott JN,Mikulis DJ,Willinski RA,Tomlinson G, terBrugge KG (2003) Idiopathic intracranial hypertension. The prevalence and morphology of sinovenous stenosis. Neurology 60 1418-1424... 

MR venography in idiopathic intracranial hypertension unappreciated and misunderstood. J Neurol Neu-rosurg Psychiatry 75 621-625... 

In a 9-year-old girl recombinant human growth hormone 6 mg/week caused idiopathic intracranial hypertension (pseudotumor cerebri), which was treated with acetazolamide [28 ]. After 4 days the dose was increased to 30 mg/kg/day, and 2 days later she developed a severe metabolic acidosis, with a pH of 7.29. 

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