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Ibuprofen HPLC analysis

D. Nicoll Griffith, M. Scartozzi, and N. Chiem, Automated deri-vatization and HPLC analysis of ibuprofen enantiomers, J. Chromatogr., /4655 253 (1993). [Pg.417]

Next, a 10 mg/kg sample of ibuprofen was administered orally to a laboratory rat. Blood samples were drawn at various times after administration of the drug and subjected to HPLC analysis. The ... [Pg.994]

Wilson, T.D. Recent advances in HPLC analysis of analgesics. J.Liq.Chromatogr., 1986, 9, 2309-2410 [also antipyrine, aspirin, buprenorphine, butorphanol, codeine, cyclazocine, diamorphine, dihydrocodeine, etorphine, fentanyl, heroin, hydrocodone, hydromorphone, ibuprofen, LAAM, levorphanol, meperidine, methadone, morphine, nalbuphine, naproxen, oxycodone, ox nnorphone, pentazocine, phenacetin, phenazocine, phenylbutazone, propoxyphene, salicylamide, salicylic acid, zomepirac]... [Pg.24]

Karnes, H.T. Rajasekharaiah, K. Small, R.E. Farthing, D. Automated solid phase extraction and HPLC analysis of ibuprofen in plasma. J.Liq.Chromatogr, 1988, 11, 489-499 [plasma SPE flurbiprofen... [Pg.767]

Figure 1.18. Comparison of MRM chromatograms following HPLC-MS/MS and UPLC-MS/ MS analysis of a mixture containing alprazolam, ibuprofen, d5-alprazolam, diphenhydramine, naproxen, and prednisolone. Each set of chromatograms was obtained from a single 100-ng/ mL injection of rat plasma. d5-Alprazolam was used as the internal standard for quantification of alprazolam. (Reprinted with pemnission from Yu et al., 2006.)... Figure 1.18. Comparison of MRM chromatograms following HPLC-MS/MS and UPLC-MS/ MS analysis of a mixture containing alprazolam, ibuprofen, d5-alprazolam, diphenhydramine, naproxen, and prednisolone. Each set of chromatograms was obtained from a single 100-ng/ mL injection of rat plasma. d5-Alprazolam was used as the internal standard for quantification of alprazolam. (Reprinted with pemnission from Yu et al., 2006.)...
An HPLC method for the analysis of etodolac and its metabolites in equine serum and urine was developed [32]. Serum (1 mL) or urine (0.5 mL) samples were extracted with iso-octane/isopropanol (95 5, v/v) after addition of ibuprofen as internal standard, diluting with 1 or 2 mL of distilled water, and adjusting the pH to 1 with 1 M HC1. The organic layer was evaporated under a stream of nitrogen, the residue dissolved in 100 pL of mobile phase, and a 20 pL aliquot injected on to the HPLC system. The HPLC system consisted of a pre-column, a 250 x 4 mm (7 pm particles) LiChrosorb RP-18 column at 25°C, isocratic elution with 1% acetic acid/acetonitrile (50 50, v/v) at a flow rate of 1.3 mL/min, and UV detector at 227 nm. The retention time of etodolac was 8.5 minutes. The method was linear over the range of 0.1-20 pg/mL in serum, and in 0.5-800 pg/mL range in urine. The limits of quantitation were 40 ng/mL in... [Pg.136]

A reversed-phase HPLC post-column ion-pair extraction system was developed by Kim and Stewart [71, 72] for the analysis of carboxylic acid drugs and their salts (sodium formate, sodium acetate, 3-bromopropionic acid, 6-aminocaproic acid, 11-bromoundecanoic acid, 1-heptanesulfonic acid, / -n i t rophcny 1 acetic acid, sodium benzoate, sodium salicylate, valproic acid, probenecid, naproxen, ketoprofen, ibuprofen, mefenamic acid, flufenamic acid, and cefuroxime sodium) using a-(3,4-dimethoxy-phenyl)-4,-trimethylammoniummethylcinnamonitrile methosulfate... [Pg.312]

See other pages where Ibuprofen HPLC analysis is mentioned: [Pg.158]    [Pg.969]    [Pg.285]    [Pg.370]    [Pg.328]    [Pg.81]    [Pg.54]    [Pg.30]    [Pg.285]    [Pg.110]    [Pg.242]    [Pg.54]    [Pg.78]   
See also in sourсe #XX -- [ Pg.244 ]



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