Ibuprofen chemical name

Ibuprofen is a well-known drug that possesses analgesic (pain-relieving) and antipyretic (fever-reducing) properties. It is particularly known for its use in pain relief from arthritis. Ibuprofen was discovered by Dr. Stewart Adams and his colleagues in the United Kingdom in the 1950s, patented in 1961, and first made available in 1969. It became available in the United States in 1974. Ibuprofen tablets are sold under the trade names Advil and Motrin. The chemical name of ibuprofen is 2-(4-isobutylphenyl)propanoic acid. 

Ibuprofen, a well-known, non-steroidal, anti-inflammatory drug (NSAID) used as a common painkiller and marketed under brand names such as Advil and Motrin , provides an example of the switching of processes from one chemical route to another. 

Naproxen is a chemical cousin of ibuprofen. Both are derived from a chemical called propionic acid. Common brand names of naproxen in the United States are Aleve , Anaprox , Naprelan , and Naprosyn . Like ibuprofen, naproxen is an NSAID that inhibits the COX enzyme and reduces pain, fever, and inflammation. The advantage of using naproxen instead of ibuprofen is that naproxen remains in the blood longer (8-12 hours... 

Advances in industrial chemical processes have allowed pharmaceutical manufacturers to take drugs that were originally marketed in racemic form and divide them into individual enantiomers, each of which may have unique properties. For some drugs, such as zopiclone, only one enantiomer (eszopiclone) is active the FDA has allowed such once-generic drugs to be patented and marketed under another name. In other cases, such as ibuprofen, both enantiomers produce the same effects. Steroid receptor sites also show stereoisomer specificity. 

Generic Name ibuprofen Trade/Proprietary Names Advil", Motrin" Chemical Structure see Figure 49.1... 

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