Hypothermia blood transfusion

The time-course suggested that the most likely cause of the arrest was the intravenous sulprostone. Contributory causes may have been hemorrhagic shock, electrolyte abnormalities, and hypothermia (from massive blood transfusion). 

Risks associated with infusion of blood products include transfusion-related reactions, virus transmission (rare), hypocalcemia resulting from added citrate, elevations in serum potassium and phosphorus concentrations from use of stored blood that has hemolyzed, increased blood viscosity from supranormal hematocrit elevations, and hypothermia from failure to appropriately warm solutions before administration. 

Total body wash-out This technique is a modification of exchange transfusion. The circulatory system is washed out with electrolyte solutions and then refilled with donor blood whilst the patient is in a state of hypothermia (G. Klebanoff et al., 1972). 

Transfusion of refrigerated blood, especially during massive transfusions or during exchange transfusions, can induce hypothermia, with a danger of cardiac arrest. If several units of blood are to be rapidly administered, they should be warmed, but not overheated, before transfusion (32). 

Other issues that must be considered with blood product administration include monitoring for transfusion-related reactions and attention to appropriate warming, particularly when large volumes are given to pediatric patients, because hypothermia is associated with increased fluid requirements and mortality." ... 

Tissue damage, blood loss, transfusions, anesthetics, hypothermia, pain, and/or anxiety that occurs perioperatively result in a mainly cell-mediated immunosuppressive state, which might influence the fate of cancer cells remaining after surgery. 

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