Hypoglycemia drug-induced

Hypoglycemia drug-induced Hypothalamic hormones Immunization agents used in Immunosuppressive medications In vitro fertilization drugs for Insomnia treatment with benzodiazepines Insulin preparations Iodine-containing products Ischemic stroke treatment of Laxatives... 

Seltzer HS. Drug-induced hypoglycemia. A review of 1418 cases. Endocrinol Metab Clin North Am 1989 18(l) 163-83. 

Of particular importance in the genatnc patient Hypoglycemia, weight gain, drug-induced disulfiram-like reaction... 

Biguanides cause hypoglycemia in 0.24 cases per 100 patient-years and it is more common when they are used in combination with a sulfonylurea (44). In 102 consecutive patients with drug-induced hospital-related hypoglycemic coma, 13 were taking metformin + glibenclamide and 3 were taking metformin + insulin (45). 

In a review of 102 consecutive drug-induced, hospital-related cases of coma, 23 were caused by insulin only, 14 by insulin + glibenclamide, and 3 by insulin + metformin (32). The likelihood of readmission for hypoglycemia after a previous admission was 2.9 times greater. 

Seltzer HS. Severe drug-induced hypoglycemia a review. Compr Ther 1979 5(4) 21-9. 

Treatment of sulfonylurea-induced hypoglycemia and of overdose with sulfonylureas has been reviewed (69). If intravenous dextrose is insufficient, octreotide is recommended (70) but not diazoxide. In patients with insulin reserve, dextrose can stimulate insulin secretion and paradoxically worsen the condition. Patients with drug-induced hypoglycemia should not be given glucagon, since it will stimulate insulin secretion. Hypoglycemia can last for up to 5 days. Continued observation is important, because recurrence after temporary recovery is common. 

Hilleman DE, Mdiiuddin SM, Ahmed IS, Dahl JM Cibeim)line-induced hypoglycemia Drug IntellClinPharm (1987) 21,38. ... 

Murad MH, Coto-Yglesias F, Wang AT, Sheidaee N, Mullan RJ, Elamin MB, Erwin PJ, Montori VM. Drug-induced hypoglycemia a systematic review. J Clin Endocrinol Metab 2009 94 741-5. 

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