Hypo taurine

Oxidation to cysteine sulfitiic acid, followed by decarboxylation to hypo-taurine and oxidation to taurine. In most tissues, it is the decarboxylation... 

L-Cysteine derivatives Taurine, hypo taurine (D 11.1) Urine... 

A second pyrimidine transferase has been found in clam tissue. This enzyme differs from thiaminase I in that it cannot use aromatic or heterocyclic amines as a pyrimidyl acceptor, but exchanges thiazole for hypo-taurine to form icthiamine (Si). 

S-cysteamine, in the presence of phenazine methosulfate. After 4 hours incubation about 50% of cysteamine is oxidized to hypo-taurine and taurine. The same result is obtained if the activity is performed in the absense of phenazine. This result is unexpected since usually the activity in the presence of cofactor is between three or five times higher than in the absence. This particular aspect merit to be investigate further in order to examine whether a natural compound is present in human liver acting as cofactor for cysteamine oxygenase. Moreover, as shown in fig. 1, a consistent portion of hypotaurine is recovered oxidized to TAU. 

Following hypo-osmotic stress there is a transient shift of taurine from the Purkinje cells to the Bergmann glial compartment, where taurine-immunoreactivity now becomes apparent (Nagelhus et al., 1993). 

Nagelhus EA, Lehmann A, Ottersen OP (1993) Neuronal-glial exchange of taurine during hypo-osmotic stress a combined immunocytochemical and biochemical analysis in rat cerebellar cortex. Neuroscience, 54, 615-631. 

The oxidation of hypotaurine to taurine Is poorly demonstrated. However recently we have been able to show the presence of hypo-... 

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