Hyperlipidemia definition

A complete history and physical examination should assess (1) presence or absence of cardiovascular risk factors or definite cardiovascular disease in the individual (2) family history of premature cardiovascular disease or lipid disorders (3) presence or absence of secondary causes of hyperlipidemia, including concurrent medications and (4) presence or absence of xanthomas, abdominal pain, or history of pancreatitis, renal or liver disease, peripheral vascular disease, abdominal aortic aneurysm, or cerebral vascular disease (carotid bruits, stroke, or transient ischemic attack). 

From the genetic viewpoint, the definition of the hyperlipidemic trait and mode of transmission requires a definition of the metabolic defect responsible for the hyperlipidemia. 

Synonyms Hydrogen sulfate Polydextran sulfate Sulfuric acid, dextran ester Definition Sulfuric acid ester of dextran Uses Binder in cosmetics pharmaceuticals (treatment for hyperlipidemia and ulcers, artery factor agent, blood coagulant) biotech applies. (DNA hybridization) industrial applies, (photographic emulsion additive)... 

IV and V) according to the definition by Fredrickson et al. (40). The elution patterns of three lipid components using the G5000PW+G5000PW column system present the characteristic feature for each type as shown in Fig. 25. Thus, these HPLC patterns obtained from whole serum in our lipid monitoring technique are very useful for diagnosis of the type for hyperlipidemia. 

Analyses of serum lipids in NPD are available in relatively few cases. From the reported data it appears that, in general, there are no specific abnormalities of serum lipids, and in particular no increase, absolute or relative, of serum sphingomyelins. Mild and often transient hyperlipidemias have been described which usually involve all lipid classes to a similar degree. In several patients of Crocker and Farber (1958) the degree of hyperlipidemia paralleled the increase in tissue lipids. It is likely that the mild hyperlipidemia in NPD represents a non-specific abnormality, but a definite answer to these questions has to await more precise information on the regulatory mechanisms of serum lipids. 

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