Hydrogen peroxide scavenging activity

Mansouri A, Makris DP and Kefalas P. 2005. Determination of hydrogen peroxide scavenging activity of cinnamic and benzoic acids employing a highly sensitive peroxyoxalate chemiluminescence-based assay structure-activity relationships. J Pharm Biomed Anal 39(l-2) 22-26. 

Siriwardhana and Shahidi [33] reported that hydrogen peroxide scavenging activities at lOOppm were 59%, 63%, and 66% and at 200ppm were 86%, 91%, and 91% for whole almond seed, brown skin, and green shell (leafy) cover extracts, respectively. The results obtained from both hazelnut and almond clearly show that extracts from by-products scavenged organic free radicals more effectively than kernel or seed extracts. 

The extracts of several oilseeds, especially borageandeveningprimrose, were evaluated for their free radicals, hydroxyl radical, superoxide and hydrogen peroxide scavenging activities. In this, 2,2-diphenyl-l-piperylhydrazyl radical PPH ) was used to monitor the efficacy of the extracts in terms of tiieir scavenging capacity. Generalized reduction reactions between DPPH and additives (AH) may be written as ... 

Pinto, P. C. A. G., L. M. L. S. Saraiva, R. Salette et al. 2005. Automatic sequential determination of the hydrogen peroxide scavenging activity and evaluation of the antioxidant potential by the 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation assay in wines by sequential injection analysis. Anal. Chim. Acta 531 25-32. 

Smirnoff, J. Colombe, S.V. (1988). Drought influences the activity of enzymes of the chloroplast hydrogen peroxide scavenging system. Journal of Experimental Botany, 39, 1097-1109. 

Cakmak, L, Strbac, D., and Marschner, H., 1993, Activities of hydrogen peroxide-scavenging enzymes in germinating wheat seeds, J. Exp. Bot. 44 127-132. 

Figure SJ Activity of the various states of the [NiFe] hydrogenase from A. vinosum as determined with a Pt electrode at 30°C.The reaction was performed in SOmM Tris/HCI (pH 8.0) in a volume of 2 ml. Oxygen was scavenged by adding glucose (90 mM) and glucose oxidase (2.5 mg/ml). Hydrogen peroxide was removed by catalase. When the system was anaerobic, an aliquot of H2-saturated water was added, and a little later enzyme (S-IOnM) was injected. Benzyl viologen (4.2mM) was used as electron acceptor.

Pramipexole is not an ergot derivative, but it has preferential affinity for the D3 family of receptors. It is effective as monotherapy for mild parkinsonism and is also helpful in patients with advanced disease, permitting the dose of levodopa to be reduced and smoothing out response fluctuations. Pramipexole may ameliorate affective symptoms. A possible neuroprotective effect has been suggested by its ability to scavenge hydrogen peroxide and enhance neurotrophic activity in mesencephalic dopaminergic cell cultures. 

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