Hydrogen bromide Bicarbonate

Chemical Reactivity - Reactivity with Water Reacts violently, forming corrosive and toxic fumes of hydrogen bromide Reactivity with Common Materials Attacks and corrodes wood and most metals in the presence of moisture. Flammable hydrogen gas may collect in enclosed spaces Stability During Transport Stable if protected from moisture Neutralizing Agents for Acids and Caustics Hood with water, rinse with dilute sodium bicarbonate or soda ash solution Polymerization Not pertinent Inhibitor of Polymerization Not pertinent. 

Chemical Reactivity - Reactivity with Water Reacts slowly generating hydrogen bromide (hydrobromic acid) Reactivity with Common Materials Decomposes rapidly in the presence of all common metals except nickel and lead, liberating heat and hydrogen bromide Stability During Transport Stable Neutralizing Agents for Acids and Caustics Rinse with sodium bicarbonate or lime... 

Pure tin is completely resistant to distilled water, hot or cold. Local corrosion occurs in salt solutions which do not form insoluble compounds with stannous ions (e.g. chloride, bromide, sulphate, nitrate) but is unlikely in solutions giving stable precipitates (e.g. borate, mono-hydrogen phosphate, bicarbonate, iodide) . In all solutions, oxide film growth occurs and the potential of the metal rises. Any local dissolution may not begin for several days but, once it has begun, it will continue, its presence being manifested... 

The most widely used sensor for chloride ions in clinical analyzers is based on an ion-exchanger, a quaternary alkylammonium chloride, dispersed in a plastic membrane. It is not an ideal sensor due to the interference of lipophilic anions (e.g., salicylates, bromides) and lip-ophylic cations (e.g., bacteriostatic agents, anesthetics) and a relatively poor selectivity towards hydrogen carbonates (bicarbonates). However, compared to charged anion- and neutral carrier-based membranes that have been tested, it is still the best-suited for automated analyzers. 

A new method for the demethylation of codeine to morphine, previously a capricious reaction, has been reported, the product being obtained in good yield. Demethylation by boron tribromide in chloroform gives 90—91%150 and by potassium t-butoxide in propanethiol gives 80% morphine.151 A patent describes an improved method for the preparation of codeinone from thebaine, by adding the alkaloid to anhydrous hydrogen bromide in solution in methylene chloride and dibutyl ether at -20 °C, in the presence of small quantities of iodine, followed by hydrolysis with aqueous sodium bicarbonate. The claimed yields of codeinone are 95% crude and 90% after purification.152 Codeinohe is an intermediate in the conversion of thebaine into codeine. An overall yield of 85% of codeine from thebaine, without purification of any of the intermediates, has been claimed for an... 

As reported by McKenzie et al. (1948), catalytic hydrogenation of I with platinum oxide leads to an allylic alcohol (II), which upon treatment with methanolic hydrochloric acid and then with concentrated hydrochloric acid proceeds through a 12-methoxy derivative to the 12-chloride (III). This substance is not isolated but rather is treated directly with bicarbonate solution, whereupon the key intermediate, methyl 3a,9a-oxido-A -cholenate (IV), can be obtained in excellent yield. The bromination product (V) (Turner et al., 1946) of the oxide is oxidized with silver chromate to the 1 l-keto-12a-bromo oxide VI, which by successive debromination, hydrogen bromide opening of the oxide to VII,... 

Hydrogen bromide Hydrogen bromide anhydrous. See Hydrobromic acid Hydrogen carbonate. See Choline bicarbonate Hydrogen 9-(2-carboxylatophenyl)-3-(2-methylanilino)-6-(2-methyl-4-sulfoanilino) xanthylium, monosodium salt. See Acid violet 9... 

Carefully neutralize spills of hydrobromic acid with a suitable agent such as powdered sodium bicarbonate, further dilute with absorbent material, place in an appropriate container, and dispose of properly. Dilution with water before applying the solid adsorbent may be an effective means of reducing exposure to hydrogen bromide vapor. Respiratory protection may be necessary in the event of a large spiU or release in a confined area. 

As shown in Scheme 12.95, the methylcarbamate was removed with hydrogen bromide (HBr) in acetic acid to form hydrobromide salt. When the amino hydrobromide salt was heated in acetic acid, a bromolactam was generated from the presumed aziridine intermediate and then treatment of the bromolactam with lithium azide in dimethylformamide produced a cis azidolactam, which then yielded the corresponding amine on reduction. Hydrolysis of the lactam with aqueous barium hydroxide ([Ba(OH)2] then produced the diamino acid, and addition of phosgene (COCI2) in aqueous sodium bicarbonate (NaHCOs) produced bisnorbio-tin, which was isolated as the corresponding methyl ester. 

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