Hydrazine 1-naphthyl

Nitrite can be deterrnined by reaction with sulfanilamide to form the diazo compound, which couples with /V-(1-naphthyl)ethylenediamine dihydrochloride to form an intensely colored red azo dye. Nitrate can be deterrnined in a similar manner after reduction to nitrite. Suitable reducing agents are cadmium filings or hydrazine. This method is useful at a nitrogen concentration of 10 -lO " M. 

Hanus recommends that )S-naphthyl hydrazine hydrochloride should be added to the solution of vanillin in such pioportion that from two to three parts are present for each part of vanillin. After standing for five hours the precipitate is transferred to a tared filter, washed with hot water until the washings no longer precipitate silver nitrate, dried at 90° and weighed. The weight of the hydrazine formed, divided by 1-92 gives that of the vanillin present. This method is avaUable in all cases where an aqueous solution of the vanillin can be prepared. 

TABLE 3. The nitrogen, the carbon-13 and carbon-14 kinetic isotope effects found for the acid-catalyzed ortho,ortho1-rearrangement of iV-naphthyl-iV-phenyl-hydrazine in 60% aqueous dioxane at 0°C... 

MoOCl2(PMe2Ph)3] reacts with 1,2-disubstituted hydrazines, PhCONHNHR, (R = Ph, 1-naphthyl, p-MeO-QH, p-Me QH4, or p-Cl-C H ) to give the red. diamagnetic crystalline molybdenum-arylimido-complexes (91). The full reports of the crystal and molecular structures of... 

To HCl-H-D-(l-naphthyl)Ala-OMe (17 190 mg, 0.715 mmol) in DMF (3mL) at 0°C was added NMM (80 pL, 0.73 mmol), followed by CDI (116 mg, 0.715 mmol). After 1 h, l-(benzyloxycarbonyl)-2-(indol-3-ylmethyl )hydrazine[321 (18 210mg, 0.711 mmol) was added, and the mixture was warmed to rt and stirred for 16 h. The mixture was poured into EtOAc and then washed sequentially with H20, sat. NaHC03, and brine, dried (Na2S04), and the solvent removed under reduced pressure. Column chromatography (20% EtOAc/hexane) of the residue afforded a foam yield 256mg (65%). 

To accelerate the reactions rates and to increase their yields, sometimes microwave-assisted procedures are applied. The first mention of using a solvent-free microwave procedure was in [55]. The authors described the synthesis of 1,3,5-triarylpyrazoline by the cyclization of chalcones with phenylhydrazine on a basic alumina solid support. The target heterocycles were synthesized under microwave irradiation in high yields (up to 85%) in 1-2 min instead of 3 h in the case of thermal activation. Another publication [56] deals with the rapid (2-12 min) solvent-phase cyclization of naphthyl-substituted chalcones 41 and hydrazines 42 in a microwave field yielding the appropriate pyrazolines 43 quantitatively (Scheme 2.10). 

NO3" -N and N02 -2 was measured on a Technican AutoAnalyzer 11 by the hydrazine sulfate reduction procedure. The reagents used were 12 g NaOH + 2 ml Brij-35 (30%)/ reduction solution 500 mg hydrazine sulfate 25 mg CUSO4 5 H2O color reagent 10 g suifanilamide, 0.8 g N-[Naphthyl-(l)]-ethylene... 

Chlor-2-methyl- benzo-[f]-chinolin) wird durch Hydrazin in Glycerin unter Entha-logenierung und Umlagerung zu 3-Methyl-5-[2-amino-naphthyl-(l)]-pyraz.ol (70°/(J d.Th. F 17Q-1710)2 reduziert ... 

The cell concentration was determined by optical density (OD) measurement at 600 nm and compared with an OD versus dry weight calibration curve. Nitrate and nitrite concentrations were measured using a segmented flow analyzer (Skalar analytic ). Nitrite detection was based on the colorimetric reaction with N-(l-naphthyl)-ethylenediamine nitrate was detected as nitrite by the same method after reduction by hydrazine. DOC was also measured using the segmented flow analyzer. Carbon compounds were detected as... 

N - [2-Amino-naphthyl. (1) ]-hydrazin-N,N. dicarbons4ure-bi8.methylamid 15 II314. 

Nightingale and Schaefer have recently described the preparation of alloxan-5-a-naphthylhydrazone by the condensation of a-naphthyl-hydrazine with 5,5-dichloro- or dibromobarbituric adds. 

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