2-Amino-4-naphthyl-5

Amino-4-naphthyl-5(p-aminophenyl) thiazoles, synthesis of, 230 orAminonitriles, condensation, with salts or esters of dithioformic and dithio-phenacetic acids, 284... 

Chlor-2-methyl- benzo-[f]-chinolin) wird durch Hydrazin in Glycerin unter Entha-logenierung und Umlagerung zu 3-Methyl-5-[2-amino-naphthyl-(l)]-pyraz.ol (70°/(J d.Th. F 17Q-1710)2 reduziert ... 

Methyl-5-[2-amino-naphthyl-(l)]- 591 l-Methyl-4-pentyl-5-hexyl- 560... 

Ai o-naplitllyl-(l)]-mercaptaa IS 1270. [8-Amino-naphthyl-(l )]-mercaptan IS II412. [1 -Amino-naphtliyl-(2)j.mercaptan 18, 681,... 

Diamino.2-[2-ammo,aQllizio]-4r[l(T)-amino-naphthyl-(2T)-amino]-bwizol 18, 337. 

CaiHggNgS, BenzaIdehyd.bis.[4-benzyUden> amino.naphthyl.(l).mercaptal] 13 1271. 

WH4JN4O, MlN -Jlthylen-bis. bis.[4.dmieiliyI> amino-phenyl].[4-amino-naphthyl.(l)1-esibi 13 U 462. 

Laotom der [2-Amino naphthyl (l)-mer capto]-es8igi aure 27 1288. 

N - [2-Amino-naphthyl. (1) ]-hydrazin-N,N. dicarbons4ure-bi8.methylamid 15 II314. 

DimethyIamino-phenyl ]- [l.methyl. amino-naphthyl-(l)]-keton 14,120. 

CnHuNgOg 4.S-Diiiitro-N-[2-ainino-phenyl> N -[l(J)-amino-naphthyl-(2 )]-phenyien diamin-(1.3) 18, 200. 

Dimethylamjna-phenyl]-bi3-[4-atM amino-naphthyl-(l)]-methan 13, 336. CaHaN [4-Diuiethyl ino-phenyll-biB. [4-athylamino-naphthyl-n)].carbifa[Pg.3097]

Various basic substances, such as aromatic amines (naphthyl-amines dissolve with difficulty in dil. HCl, diphenylamine only in cone. HCl, triphenylamine insoluble) nitro-anilines some amino-carboxylic acids. 

Amino acids react in alkaline solution with a-naphthyl isocyanate to yield the sodium salts of the corresponding a-naphthylureido acids, which remain in solution upon addition of a mineral acid, the ureido acid is precipitated. 

Amino Acid MJ. Benzoate 3 5-Dlnltro-benzoate Phenyl-uieldo Acid />-Toluene- sulphonate 2 4-Dicbloro-phenoxy-acetate a-Naphthyl-nreldo Acid Phthalyl Derivative... 

Amino-5 -deoxy-2, 3 -0-isopropylideneadenosine was acylated at N-5 with an activated derivative of the 6-carboxy-2-naphthyl ester of Kemp s acid imide. The resulting molecule possesses self-complementary binding sites, the key feature of replicating molecules that act as templates for their own reproduction. The dimer of this molecule is, however, not very stable K = 630 L mol ). When the two initially mentioned educts are added, a small proportion of the ternary complex is also formed and undergoes a fast, template-catalysed... 

On the other hand there have been isolated salts of either the acyclic amino ketone form or the cyclic enamine form, namely 6-methylamino-l-a-naphthyl-l-hexanone (95, = 5) and 12-methylamino-l-a-naphthyl-l-dodecanone (95, n=ll), or l-methyl-2-a-naphthyl-l-aza-2-cycloheptene... 

The rationale for the predominance of linear cyclization products versus angular cyclization products has been accepted as qualitative." The mechanism of the Combes reaction has been argued. It was initially proposed that cyclization to linear products was due to initial protonation of a more reactive site on the aromatic ring (1-position of 13 corrresponding to the 10-position of 15) thus, blocking cyclization to angular products. Bom showed this not to be the case for the cyclization of 2-naphthyl amino-2-penten-4-one. No 10-deutero material was observed. 

The two best selectors resulting from Li s screening, DNB-L-ala and DNB-L-leu, were then prepared on a larger scale, attached to silica beads modified with 3-amino-propyl-triethoxysilane, and the CSPs were packed into columns. Respective separation factors of 4.7 and 12 were found for the separation of racemic naphthyl leucine ester 17 using these CSPs. 

Fig. 7-6). Two unichiral amides which have been known capable of this reaction are 1-phenylethylamine [15] and l-(l-naphthyl)ethylamine [16]. Marfey s reagent [N-a-(2,4-dinitro-5-fluorophenyl)-L-alaninamide] was introduced as a reagent to deriva-tize amino acids with cyclopentane, tetrahydroisoquinoline or tetraline structures [17]. Simple chiral alcohols such as 2-octanol can also be used to derivatize acids such as 2-chloro-3-phenylmethoxypropionic acid [18]. 

Dinitronaphthalene (Delta-dinitronaphtha-lenet 1,6-DNN). Crysts from acet ac, mp 166-67°, bp at 10mm 235°, 360° with decompn (Refs 2 31) CA Registry No 60746-5. It is prepd by the nitration of 2-nitronaphtha- ene with nitric ac/sulfuric ac in hot acet ac (Ref 21) by diazotization of 5-nitro-2-naphthyl-amine followed by treatment of the diazonium salt with Na cobaltinitrite, yield 40% (Ref 36) or by removal of the amino group from 1,6-dinitro-2-naphthylamine by diazotization followed by redn (Ref 17). The temp of expin is 492°(Refl7)... 

Fischer alkenylcarbene complexes undergo cyclopentannulation to alkenyl AT,AT-dimethylhydrazones (1-amino-1-azadienes) to furnish [3C+2S] substituted cyclopentenes in a regio- and diastereoselective way along with minor amounts of [4S+1C] pyrrole derivatives. Enantiopure carbene complexes derived from (-)-8-(2-naphthyl)menthol afford mixtures of trans,trans-cycloipentenes and ds,ds-cyclopentenes with excellent face selectivity [75]. The mechanism proposed for the formation of these cyclopentene derivatives is outlined in Scheme 28. The process is initiated by nucleophilic 1,2-attack of the carbon... 

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