Hydrastis Canadensis

Meconin, C10H10O4, was isolated from opium in 1832 by Dublanc, and also occurs in Hydrastis canadensis. It crystallises from water in prisms, m.p. 102°, and dissolves in alkaline solutions, forming unstable salts of meconinic acid, CioHjgOg, of which it is the lactone. It was-... [Pg.200]

Rehman, J. et al., Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis, Immunol Lett, 68, 391,1999. [Pg.200]

Mahady GB, Pendland SL, Stoia A, Chadwick LR. (2003) In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. Phytother Res 17 217-221. [Pg.496]

Gentry EJ, Jampani HB, Keshavarz-Shokri A, Morton MD, Velde DV, Telikepalli H, Mitscher LA, Shawar R, Humble D, Baker W. (1998) Antitubercular natural products Berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifen-dine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2. J Nat Prod 61 1187-1193. [Pg.516]

Hwang, B.Y. et al., Antimicrobial constituents from goldenseal (the rhizomes of Hydrastis canadensis) against selected oral pathogens, Planta Med., 69, 623, 2003. [Pg.731]

Chaulmoogra, hydnocarpus) Hydrastis canadensis (Goldenseal, Indian dye) Hypericum perforatum (St. John s wort, Klamath weed) Ignatia amara... [Pg.134]

The incorporation of dopa (60) has been further studied by examining its utilization in the formation of berberine (66) and hydrastine (67) in Hydrastis canadensis, corydaline (68) and protopine (70) in Corydalis solida, and ochotensimine (71) and protopine (70) in C. ochotensis.20 [2-14C]Dopa [as (60)] was again found to label only the isoquinoline moiety of these alkaloids (label is shown by ). [Pg.12]

Even given that the formation of (-) reticuline cannot be blocked, there may be opportunities to block the biochemical sequences leading to thebaine, or even to splice in mechanisms leading to nonaddictive alkaloids produced from (-) reticuline by other plants—for example, berberine ex Hydrastis canadensis or protopine ex Fumaria officinalis. [Pg.385]

Schieffer, G. and Kohn, M. 2002. HPLC assay of Echinacea purpurealGolAtustal (Hydrastis canadensis) combination formulations for the phenolic acids, alkylamides, alkaloids. J. Liq. [Pg.171]

Norlaudanosoline [166) R = H] has for a long time been regarded, in schematic terms, as the biogenetic precursor of the isoquinoline alkaloids, and since it is now known158 that noradrenaline [(167) R = OH] is incorporated into berberastine (168) in Hydrastis canadensis L., presumably via 4-hydroxynorlaudanosoline [(166) R = OH], it is possible159 that a series of alkaloids exists based on 166 (R = OH) as parent. It is significant in this context that the alkaloids imenine... [Pg.326]

Cactaceae Hydrastinaceae Leguminosae Coryphantha macro-meris var. runyonii Hydrastis canadensis Albizzia julibrissin Mimosa pudica 331 220 105 105... [Pg.103]

C. thalictrifolia (Papaveraceae), Hydrastis canadensis (golden seal) (Ranunculaceae)... [Pg.95]

Coelocline sp. (Annonaceae), Berberis vulgaris, B. sp., Hydrastis canadensis, Mahonia sp., Nandina sp. (Berberidaceae), Archangelica sp. (Menispermaceae), Argemone sp., Chelidonium sp., Corydalis sp. (Papaveraceae), Coptis chinensis, C.japonica, Thalictrum sp. (Ranunculacae), Evodia sp., Toddalia sp., ifanthoxylum sp. (Rutaceae)... [Pg.358]

Umbellatine) vulgaris, B. sp., Hydrastis canadensis, AChE, ATPase, BChE,... [Pg.491]

Additional oxidative coupling processes among the various methylated derivatives of laudanosoline yield many other families of bases, including the pavine argemonine (88) from Argemone mexicana E berberine (89) from Hydrastis canadensis E which, despite its toxicity, has been used as an antimalarial protopine (90) and chelidonine (91) from Chelidonium majus E rhoeadine (92) and the cephalotaxus ester harringtonine (93) from Japanese plum yews ( Cephalotaxus spp.), which is a compound of some significance because it possesses potent antileukemic activity (see Fig. 3). [Pg.545]

An alkaloid obtained from hydrastis, the dried rhizome and roots of golden seal, Hydrastis canadensis (Ranunculaceae). Crystals. M.p. 132°. [Pg.663]

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