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Vector hybrid

FIGURE 13.6 Viral-nonviral hybrid vectors. DNA is bound to a poly-L-lysine (PLL)-trans-ferrin conjugate (A) to form a PLL-transferrin-DNA complex (B). Transferrin binds to specific receptors on the surface of some cancer cells, thereby targeting gene delivery to these cells (C). [Pg.360]

Schmidt-Wolf, G.D., Schmidt-Wolf, I.G. (2003). Non-viral and hybrid vectors in human gene therapy an update. Trends Mol. Med., 9(2), 67-72. [Pg.369]

Hildinger, M. et al. (2001). Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer. J. Virol. 75, 6199-6203. [Pg.52]

Kakizawa Y, Miyata K, Furukawa S, Kataoka K (2004) Size-controlled formation of a calcium phosphate-based organic-inorganic hybrid vector for gene delivery using poly(ethylene glycol)-Woc -poly(aspartic acid). Adv Mater 16(8) 699-702... [Pg.61]

Hybrid vectors consisting of adeno-associated virus (AAV) vectors enclosed in liposomes lead to alO-fold increase in transduction efficiency compared to liposomes containing plasmid DNA and 6-fold increase compared to AAV vector alone [409],... [Pg.490]

Lieber A, Steinwaerder DS, Carlson CA, Kay MA. 1999. Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes. J. Virol. 73 9314-24... [Pg.438]

Some hybrid vectors for recombinant DNA techniques in Yeast... [Pg.179]

Hybrid vector Bacterial plasmid component Yeast nuclear component Yeast plasmid component... [Pg.179]

Hybrid vectors Puhnouary hyperteusiou Alzheimer s disease... [Pg.3326]


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