Hyaluronan oligosaccharides

Melrose, J., Tammi, M., and Smith, S., Visualisation of hyaluronan and hyaluronan-binding proteins within ovine vertebral cartilages using biotinylated aggrecan Gl-link complex and biotinylated hyaluronan oligosaccharides, Histochem. Cell Biol., 2002 117, 327, 2002. 

Fieber, C. et al., Hyaluronan-oligosaccharide-induced transcription of metalloproteases, J. Cell Sci., 117, 359, 2004. 

Xu, H. et al., Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72, J. Biol. 

DeAngelis PL, Oatman LC, Gay DF. Rapid chemoenzymatic synthesis of monodisperse hyaluronan oligosaccharides with immobilized enzyme reactors. J. Biol. Chem. 2003 278 35199-35203. 

Knudson W, Casey B, Nishida Y, Eger W, Kuettner KE, Knudson CB. Hyaluronan oligosaccharides perturb cartilage matrix homeostasis and induce chondrocytic chondrolysis. Arthritis Rheum 2000 43 1165-1174. 

Rahmanian, M. Pertoft, H. Kanda, S. Christofferson, R. Claesson-Welsh, L Heldin, P. Hyaluronan oligosaccharides induce tube formation of a brain ouiotiieliid cell line in vitro. Exp. Cell Res. 1997.237,223-230. 

Russo RIC, Garcia MG, Alaniz L, Blanco G, Alvarez E, Hajos SE. Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P-glycoprotein activity and P13K/Akt pathway. Int J Cancer. 2008 122 1012-8. 

At the same time, as was mentioned [106], some hyaluronan oligosaccharides can participate in the gene switching at the early stages of the cellular cycle initiation, that is, can fulfil regulatory functions. Thus, in all likelihood, nuclear HA participates in the structural... 

Maccaii, R, Tripodi, F., Volpi, N. (2004) High-performance capillary electrophoresis of hyaluronan oligosaccharides produced hyaluronate lyase. Carbohydrate Polymers, 56, 55-63. 

Montesano R, Kumar S, Orci L and Pepper MS. S)mergistic effect of hyaluronan oligosaccharides and vascular endothelial growth factor on angiogenesis in vitro. Lab Invest 75 249-62, 1996. 

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