Hyaluronan medical applications

T. C. Laurent, The Chemistry, Biology and Medical Application of Hyaluronan and Its Derivatives. Portland Press, London, 1998. 

Biology, and Medical Applications of Hyaluronan and Its DerivativIsC. Laurent, ed., Portland Press, London, 43-65. 

Laurent, T. C. The chemistry, biology and medical applications of hyaluronan and its derivatives. London Portland Press, 1998. 

Balazs EA, Leshchiner E, Larsen N, Band P. Hyaluronan biomaterials medical applications. In Wise DL, ed. Handbook of Biomaterials and Applications. New York Marcel Dekker Inc., 1995 1693-1715. 

Asari A. Medical application of hyaluronan. In Garg HG, Hales CA, eds. Chemistry and Biology of Hyaluronan. Amsterdam Elsevier, 2004 457 73. 

The first medical application of the noiiinflammators fraction of Na-hyaluronan (NIF-NaHY) was in the ophthalmic surgery. The commercial product under the trademark Healon was introduced by Kabi Pharmacia, Upsala, Sweden. Healon is primarily used in cataract surgery. It minimizes the surgical trauma during the removal of the cataractous lens and introduction of its replacement, the intraocular plastic lens. 

Desehrevel, B. (in press). Hyaluronan Its unique ehemieal, physieoehemieal and biological properties make it an applieation-rieh system. In Medical Applications of Polymers. M. Popa, R. M. Ottenbrite, and C. V. Uglea (Eds.). American Scientific Publishers, Los Angeles, U.S. 

The wide range of practical medical applications of hyaluronan continues to be based upon its anti-inflammatory, disinfectant and wound healing effects. HA promotes epithelial regeneration prevents the formation of granulation tissue, adhesions and scars reduces swelling and itching normalizes blood circulation promotes scarring of venous ulcers and protects internal eye tissue [24]. 

Heinegard, D., Bjomsson, S., Morgelin, M., Sommarin, Y. (1998) Hyaluronan-binding matrix proteins, in, The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives (ed. T.C. Laurent), Portland Press, London. 

Upon first glance, it may appear this chapter is oversaturated with technological details that would be of interest only to technologists working in hyaluronan production. However, the material is presented in this way intentionally in order to properly elucidate the difficulties of hyaluronic acid production and the potential problems caused by the technological impurities in the final product when intended for medical application. 

Medical Applications of Hyaluronan 171 Table 6.3 Hyaluronan products for treatment of osteoarthrosis... 

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