Human body sucrose, effects

Acesulfame-K. This substance (potassium salt of the cyclic sulfano-mide), 6-methyl-l,2,3-oxatJiiazine-4(3H)-l,2.2-dioxide, shown below, was developed by Karl Clauss (IloechstCelanese Corporation, Somerville, New Jersey) in 1967. The compound is a white, odorless, crystalline substance with a sweetening power 200 times that of sucrose. A synergistic effect is produced when the substance is combined with a number of other sweeteners. The substance is calorie-free and not metabolized in the human body. Approval of the use of Acesulfame-K was given by the Food and Drug Administration ( FDA) in the United States in 1983 and it is found in scores... 

Most forms of Cr(III) are not absorbed and utilized by the body. For this reason, and because of the increased use of sucrose and other refined foods, a marginal human chromium deficiency may be widespread.604 605 This may result not only in poor utilization of glucose but also in other effects on lipid and protein metabolism.597 However, questions have been raised about the use of chromium picolinate as a dietary supplement. High concentrations have been reported to cause chromosome damage606 and there may be danger of excessive accumulation of chromium in the body.607... 

Although data on the toxicology of sucrose esters in humans is less common than in animal models, some studies are reported. A pharmacokinetic study of human volunteers fed 1 g of sucrose tallowate showed no adverse effects, and plasma and urine analyses indicated rapid hydrolysis of the ester in the gastrointestinal tract and almost complete absorption and subsequent excretion of the hydrolysis products. This indicated Kttle tendency for the ester to accumulate in body tissues [79]. 

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