How Nature makes fatty acids

If the reagent is too precious to waste, another device is to use two molecules of base for every one of the compound. In this way there is always a molecule of strong base waiting to remove a pro-, ton from the product. The acylation of sulfones with esters is a good example. 

The product has a more acidic hydrogen atom (green) than any in the starting material so it could protonate the origin nal anion. Using two equivalents of base avoids this. 

By this device good yields of keto-sulfone can be formed even when both partners are aliphatic compounds with acidic protons. 

This is a good way of making stabilized ylidoiB for the Wittig reaction Bee -p.aiT. 

Fatty acids are big news, whether saturated or unsaturated. Too much saturated fatty acid seems to be bad for us, clogging arteries, while some unsaturated fatty acids seem to protect us against that fatal condition. There are hundreds of fatty acids in living things but most have one special characteristic—they have an even number of carbon atoms. Here are two of the most frequently found fatty acids. 

TIvs is. a gpod way of tr kirg stf lli ylklos fortii WItligroaetion see-p. i7. i  

---

Asymmetric synthesis ch41 and protect sensitive functional groups How to make and manipulate sugars and their derivatives Lipids form the basis of membrane structures The main sorts of natural products are alkaloids, polyketides, terpenes, and steroids Alkaloids are amines made from amino acids Fatty acids are built up from acetyl CoA and malonyl CoA subunits ... 

---