Host components surfaces using

RECOGNITION PHENOMENA AT SURFACES USING PHOTOISOMERIZABLE GUEST OR HOST COMPONENTS... 

Sialic acids are a family of nonulosonic acids that have been predominantly found as the outermost carbohydrate units on glycoproteins and glycolipids of vertebrates, or as components of polysaccharides in certain types of bacteria (I, 2). Sialic acids play vital roles in a variety of physiological and pathological processes in vertebrates, such as cellular recognition and communication (1, 2). They are also believed to be important virulence factors in bacteria, used by bacteria to mimic sialylated host cell surface carbohydrate structures to evade detection and attacking by the immune defense mechanisms of the host (3-6). 

Very recently, a novel and versatile method has been reported for the construction of stable, zero-valent metal quantum dots, using dendrimers as well-defined nano-template/containers. The concept involves the use of dendrimers as hosts to preorganize small molecules or metal ions, followed by a simple in situ reaction, which immobilizes and incarcerates these nanodomains (Figure 17) [89]. The size, shape, size distribution, and surface functionality of the dendritic nanocomposites are determined and controlled by the architecture. Dendrimer-based nanocomposites display unique physical and chemical properties as a consequence of the atomic/molecular level interactions between the guest and host components within the dendrimer as well as the dendrimer interaction with various solvents and media. 

Anti-adhesive effect. Green and roasted coffee, used in a treatment mixture and as a pretreatment on beads, inhibited the Strep tococcus mutans sucrose-independent adsorption to saliva-coated hydroxyapatite beads. The inhibition of Salmonelb mutans adsorption indicated that coffee-active molecules may adsorb to a host surface, preventing the tooth receptor from interacting with any bacterial adhesions. Among the known tested coffee components, trigonelline and nicotinic and chlorogenic acids are very... 

Neither the mechanisms of the host defence for eradication of challenging Salmonella bacteria, nor the relative importance of the host defence against the various Individual surface components of the bacterial cell envelope are well understood. Since, as was stated above, the O-antlgenic polysaccharide chains apparently play an important role in eliciting an effective host defence of either humoral or cellular nature, we have used the various saccharides described earlier for studies of this problem. 

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