Hivid - Zalcitabine

Hivid Zalcitabine 0.375, 0.75 mg Tablet HIV A synthetic nucleoside analog (DNA replacement) Lactose, MCC < croscarmellose Na, magnesium stearate, hypromellose, PEG, polysorbate 80 Roche... 

Hivid (Zalcitabine). Roche Products Ltd UK Summary of product characteristics, November 2004. 

Hivid (Zalcitabine). Roche Pharmaceuticals. US Prescribing information, September 2002. Aweeka FT, Gambertoglio JG, van der Horst C, Raasch R, Jacobson MA. Pharmacokinetics of concomitantiy administered foscarnet and zidovudine for treatment of human immunodeficiency virus irifection (AIDS clinical trials group protocol 053). Antimicrob Agents Chem-other(l992)36,1773-8. 

Zalcitabine (ddC) Hivid (anticipated discontinuation of distribution in 2006) 0.375-, 0.75-mg tab 0.75 mg tid CrCI Dose (mL/minute) 10-40 0.75 mg bid less than 10 0.75 mg qday No data on hemodialysis None Peripheral neuropathy stomatitis, lactic acidosis with hepatic steatosis (rare but potentially life-threatening toxicity with use of NRTIs) pancreatitis Renal excretion... 

Zalcitabine (ddC, Hivid) is a cytidine analogue active against HIV-1, HIV-2, and hepatitis B virus. It is used for the treatment of HIV infection in adults and asymptomatic children as part of a multidrug regimen. It may be less effective than the other nucleoside inhibitors and is used less frequently. 

Zalcitabine/Hivid (ddC) 0.375 or 0.75 mg tablets 0.75 mg t.i.d. Peripheral neuropathy, lactic acidosis with hepatic steatosis 0.08... 

Zagreb antivenom is a non-proprietary antivenom preparation that can be used as an injected ANTIDOTE to the poison from an adder s bite. However, the systemic allergic and other effects of the venom are rarely serious enough to warrant the use of the antivenom, zalcitabine [ban, inn, usan] (ddC DDC Hivid ) is a synthetic nucleoside analogue, a REVERSE TRANSCRIPTASE INHIBITOR which acts as an ANTIVIRAL AGENT. It is active orally as an ANTI-HIV AGENT. 

NRTIs are faulty version reverse transcriptase. Reproduction of HIV is stalled when HIV uses NRTI instead of the normal reverse transcriptase. Dmgs within this category include Abacavir (Ziagen, ABC), Abacavir, Lamivudine (Epzicom), Abacavir, Lamivudine, Zidovudine (Trizivir), Didanosine (Videx, ddl, Videx EC), Emtricitabine (Emtriva, FTC, Coviracil), Emtricitabine, Tenofovir DF (Truvada), Lamivudine (Epivir, 3TC), Lamivudine, Zidovudine (Combivir), Stavudine (Zerit, d4T), Tenofovir DF (Viread, TDF), Zalcitabine (Hivid, ddC), and Zidovudine (Retrovir, AZT, AZV). 

Stavudine Zerit Zalcitabine Hivid Zidovudine Retrovir... 

AZT has an alternative name of zidovudine and is sold under the brand name of Retrovir. Other similar compounds that have been approved for AIDS therapy include ddl (2, 3 -dideoxyinosine - didanosine, Videx) and DDC (2, 3 -dideoxycyti-dine-zalcitabine, HIVID). They are fakes for G (guanoside) and C (cytosine), respectively. 

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