Activity of analogues

Andrews DM, Cherry PC, Humber DC, Jones PS, Keeling SP, Martin PE, Shaw CD, Swanson S (1999) Synthesis and influenza virus siahdase inhibitory activity of analogues of 4-guanidino-Neu5Ac2en (Zanamivir) modified in the glycerol side-chain. Eur J Med Chem 34 563-574... 

L Berlicki, A Obojska, G Forlani, P Kafarski (2005) Design, Synthesis, and Activity of Analogues of Phosphinothricin as Inhibitors of Glutamine Synthetase, J Med Chem 48(20) 6340-6349... 

The tumor-inhibitory activity of analogues of purine and pyrimidine bases led Shealy and several coworkers to synthesize a series of analogues of the imidazoles in the biosynthetic pathway to purine ribonucleotides and to test these analogues for antineoplastic effects. 59 Beginning... 

Brackett, S., Waletzky, E., and Baker, M. (1946). The relation between pantothenic add and Plasmodium gallinaceum infections in the chicken and the antimalarial activity of analogues of pantothenic acid.. Parasitol. 32, 453-462. 

Chandrakumar, N.S., Yonan, P.K., Stapeffeld, A., Svage, M., Rorbacher, E., et al. (1992) Preparation and opioid activity of analogues of the analgesic dipeptide 2,6-dimethyl-L-tyrosyl-N-(3-phenylpropyl)-D-alanylamide. J. Med. Chem. 35 223-233. 

Two long papers have dealt with syntheses and biological activities of analogues of cyclophosphamide (CPA) and of aldophosphamide. Scheme 12 indicates simple reactions which have been carried out on the ether (91) the products were... 

Binder, D., et al. Analogues and derivatives of tenoxicam. 1. Synthesis and antiinflammatory activity of analogues with different residues on the ring nitrogen and the amide nitrogen. J. Med. Chem. 1987, 30, 678-682. 

Delfoume, E., Darro, R, Bontemps-Subielos, N., Decaestecker, Ch., Bastide, J., Fryd-man. A., Kiss, R. (2001). Synthesis and Characterization of the Antitumor Activities of Analogues of Meridine, a Marine Pyridoacridine Alkaloid, J. Med. Chem., 44. 3275-3282. 

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