Historical Perspectives of Cancer Risk Assessment

Of particular note (1) These first guidelines called for revising each risk assessment as better information became available, a goal that has been rarely realized. (2) Gaps in scientific knowledge were to be filled with public health protective assumptions to err on the side of safety, an early application of the precautionary principle. 

TABLE 1.1. Historical Perspectives of the Development of the Risk Assessment Process 

Community Exposure to Vinyl Chloride (Kuzmack and McGaughy 1975) 

United States. Interagency Regulatory Liaison Group (IRLG 1979b) 

This was the first risk assessment document to be completed by the EPA. 

---