Histamine intoxication

Uragoda, C.G. and Lodha, S.C. (1979). Histamine intoxication in a tuberculosis patient after ingestion of cheese. Tubercle, 60, 56. 

Examples of amines that frequently occur in fish muscle include cadaverine from lysine, putrescine from ornithine and histamine from histidine. Histamine, because of its involvement in Scombroid food poisoning (histamine intoxication), has been extensively studied with respect to factors influencing its formation in many different fish species. Tuna and other fish from the families Scomberesocidae and Scombridae and a non-scombroid fish, mahi-mahi (dolphin fish) have been most... 

Uragoda CG. Histamine intoxication with isoniazid and a species of fi. Ceylon MedJ (1978) 23,109-10. 

Isoniazid is a potent inhibitor of histaminase, and if taken together with tuna or other fishes or cheese, it may give rise to symptoms corresponding to histamine intoxication (Uragoda 1980 Uragoda and Kottegoda 1977 Uragoda and Lodha 1979). 

Taylor SL, JE Stratton, JA Nordlee (1989) Histamine poisoning (scombroid fish poisoning) an allergy-like intoxication. Clin Toxicol 27 225-240. 

A meta-analysis of 24 studies showed that cimetidine and ranitidine, but not famotidine or nizatidine, caused small increases in blood alcohol concentrations (19). The mechanism is unclear, but one possibility is inhibition of gastric alcohol dehydrogenase. However, relative to accepted legal definitions of intoxication the effect of any histamine receptor antagonist on blood alcohol concentrations is unlikely to be clinically significant. 

A relationship between putrescine, cadaverine, and histamine was suggested as responsible for numerous cases of food intoxication... 

The deliberate or accidental ingestion of natural belladonna alkaloids is a major cause of poisonings. Many histamine Hj-receptor antagonists, phenothiazines, and tricyclic antidepressants also block muscarinic receptors, and in sufficient dosage, produce syndromes that include features of atropine intoxication. 

Taylor, S. L., Stratton, J. E., and J. A. Nordlee. (1989). Histamine poisoning (Scombroid fish poisoning) An Allergy-like intoxication. Clin. Toxicol. 27, 225-240. 

Great combination effects of such compounds had been hoped for, but this seems only to be the case for drug-analogous crown compounds with strong antiulcer-ogenic effects against histamine-induced ulcers [287,288]. Decontaminating effects of crown compounds in heavy metal intoxication have also been reported [289]. 

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