Hippomane mancinella

I), myoporoides, Nicotiana tabacum (tobacco), N. spp., (Solanaceae) metabolite of Nicotine Hippomane mancinella (Euphorbiaceae), Physostigma venenosum (calabar bean) (Fabaceae) [seed]... 

Hippomane mancinella (Euphorbiaceae), Physostigma venenosum (Calabar bean) (Fabaceae) [seed]... 

Hippomane mancinella (manchineel apple), Hura crepitans (Euphorbiaceae) [fruit, leaf latex], Pimelea simplex, Wikstroemia retusa (Thymelaeaceae)... 

Koppaka, V.R., Toxic principle of Hippomane mancinella. II. Structure of hipppomanin A, Lloydia, 40, 169-171, 1977. 

Mandnellin. C36H52O8, Mr 612.80, ester of 6,7-epoxy-4,5,9,13,20-pentahydtoxy-1 -tiglien-3-one, a diterpene of the tigliane type. M. can be isolated firom the Hippomane mancinella (Euphorbiaceae) growing in... 

Green coffee beans contain a D-glucopyranosyl ester (cofaryloside) which chemical and spectroscopic evidence identified as l-0-(9p,16a,17-trihydroxy-kauran-18-oyl)-p-D-glucopyranose, and 2, 3-di-0-decanoyl-2-0-octanoyl-6-0-succinoyl-aa-trehalose has been isolated from the lipids of Mycobacterium paraf-finicum Hippomanin A, a toxic principle from Hippomane mancinella, has... 

A) The manganas (apples) or manganillas (little apples), from which the poison was made, came from the ill-reputed machineel tree, Hippomane mancinella L. (Euphorbiaceae). Especially noteworthy is the attempt by Enciso to determine the effects of the poison—it is probably one of the earliest experiments reported in the literature that may properly be termed pharmacological. The unpleasant nature of the plant is due to the presence in its latex of a complex mixture of potent pro-inflammatory and tumor-promoting esters of various diterpene alcohols (20, 21). 

C) The intention seems to be to emphasize the frightful nature of the poison as compared with merely being eaten aliue peecemeale Unfortunately, the wapototo plant that yielded this poison has not been identified—it might have been Hippomane mancinella or Hura crepitans or some related species. 

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