High-speed centrifugal countercurrent chromatography

Ito, Y. Sandlin, J.L. Bowers, W.G. High-speed preparative countercurrent chromatography (CCC) with a coil planet centrifuge. J. Chromatogr. 1982, 244, 247-257. 

Source From Coil planet centrifuges for high-speed counter-current chromatography, in Countercurrent Chromatography ... 

Ito, Y. Menet, J.-M. Coil Planet Centrifuges for High-Speed Countercurrent Chromatography. In Countercurrent Chromatography Menet, J.-M., Thiebaut, D., Eds. Marcel Dekker New York, 1999 87-119. 

Figure 11.13. Design principle of the multilayer coil planet centrifuge for high-speed countercurrent chromatography. (From ref. [235]. John Wiley Sons)...

Ito, Y. Menet, J.-M. Coil planet centrifuges for high-Speed countercurrent chromatography. In Countercurrent... 

Countercurrent chromatography (CCC), because it uses no solid support in the separation colmnn, is particularly suitable for the separation and purification of peptides which often present a problem of irreversible adsorption onto solid supports. Since the 1970s, the horizontal flowthrough coil planet centrifuge (CPC) has been used for the separation of a variety of natural and synthetic peptides. High-speed which was developed in the 1980s,... 

Countercurrent chromatography (CCC) is a liquid-liquid partition technique that does not involve use of a solid support. In high-speed countercurrent chromatography (HSCCC), one of the two immiscible liquid phases (the stationary phase) is retained in an Ito multilayered coil column by centrifugal force while the other liquid phase (the mobile phase) is pumped through the rotating column. A variation of HSCCC, known as... 

High-speed coxmtercurrent chromatography (HSCCC) and centrifugal partition chromatography (CPC) refer to particular types of hydrodynamic and hydrostatic sohd support-free chromatographic systems, respectively. Countercurrent chromatography was firstly introduced by Ito, Harada, and Aoki in 1966 [6], while... 

High-speed countercurrent chromatography (HSCCC) is a relatively new technique. It is a liquid-liquid partitioning chromatographic method in which the stationary phase is immobilized by a centrifugal force. HSCCC is the most advanced form of CCC in terms of partition efficiency and separation time. As solvent system, a mixture in different ratio is usually used, depending on the flavonoids nature ethyl acetate/... 

---