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Hexose-6-phosphate dehydrogenase

Hexose 6-phosphate dehydrogenase and 11 p-hydroxysteroid dehydrogenase type 1... [Pg.398]

Banhegyi G, Benedetti A, Fulceri R, Senesi S. Cooperativity between 1 If -hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in ttie lumen of ttie endoplasmic reticulum. J. Biol. Chem. 2004 279 27017-27021. [Pg.400]

E, White PC, Hewison M, Mason PJ, Connell JM, Shackleton CH, 49. Stewart PM. Mutations in the genes encoding 11 P-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Nat. Genet. 50. 2003 34 434-439. [Pg.401]

San Millan JL, Botella-Carretero JI, Alvarez-Blasco F, Luque-Ramirez M, Sancho J, Moghetti P, Escobar-Morreale HF. A 51. study of the hexose-6-phosphate dehydrogenase gene R453Q and... [Pg.401]

Lack of association of the 11 P-hydroxysteroid dehydrogenase type 53. 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen... [Pg.401]

Lavery GG, Walker EA, Draper N, Jeyasuria P, Marcos J, Shackleton CH, Parker KL, White PC, Stewart PM. Hexose-6-phosphate dehydrogenase knock-out mice lack 11 P-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation. J. Biol. Chem. 2006 281 6546-6551. [Pg.401]

Hewitt KN, Walker EA, Stewart PM. Minireview hexose-6-phosphate dehydrogenase and redox control of 11 P-hydroxysteroid dehydrogenase type 1 activity. Endocrinology 2005 146 2539-2543. [Pg.401]

Liu Y, Nakagawa Y, Wang Y, Liu L, Du H, Wang W, Ren X, Lutfy K, Friedman TC (2008) Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice. J Mol Endocrinol 41(2) 53-64... [Pg.3823]

London E, Lala G, BCTgCT R, Panzenbeck A, Kohli AA, Renner M, Jackson A, Raynor T, Loya K, Castonguay TW (2007) Sucrose access differentially modifies 1 ip-hydroxysteroid dehydrogenase-1 and hexose-6-phosphate dehydrogenase message in liver and adipose tissue in rats. J Nutri 137 2616-2621... [Pg.3824]

Houttuynia cordata, 3587 H6PDH, See Hexose-6-phosphate dehydrogenase (H6PDH)... [Pg.4200]

Bublitz C, Lawler CA. The levels of nicotinamide nucleotides in liver microsomes and ttieir possible significance to the function of hexose phosphate dehydrogenase. Biochem. J. 1987 245 263-267... [Pg.400]

The basis of the action of iodoacetate on muscle contraction was uncovered by Dickens and Rapkine (ca. 1933). They found iodoacetate alkylated SH groups on proteins, especially those in glyceraldehyde 3-phosphate dehydrogenase (G-3-PDH). When the enzyme was inhibited precursors accumulated—hexose mono- and diphosphates—as in Lundsgaard s experiments. [Pg.54]

Reactions of the hexose monophosphate pathway. Enzymes numbered above are 1) glucose 6-phosphate dehydrogenase and 6-phosphogluconolactone hydrolase, 2) 6-phosphogluconate dehydrogenase,... [Pg.144]

FMN was first identified as the coenzyme of an enzyme system that catalyzes the oxidation of the reduced nicotinamide coenzyme, NADPH (reduced NADP), to NADP (nicotinamide adenine dinucleotide phosphate). NADP is an essential coenzyme for glucose-6-phosphate dehydrogenase which catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconrc acid. This reaction initiates the metabolism of glucose by a pathway other than the TCA cycle (citric acid cycle). The alternative route is known as the phosphoglneonate oxidative pathway, or the hexose monophosphate shunt. The first step is ... [Pg.1699]

Figure 18.10 The hexose monophosphate shunt pathway. A, glucose-6-phosphate dehydrogenase B, 6-phosphogluconate dehydrogenase C, pentose-5-phosphate iso-merase D, pentose phosphate epimerase E, transaldolase F, transketolase G, phospho-hexoseisomerase. (Reproduced by permission from Williams JF. A critical examination of the evidence for the reactions of the pentose pathway in animal tissues. Trends Biochem Sri December 316, 1980.)... Figure 18.10 The hexose monophosphate shunt pathway. A, glucose-6-phosphate dehydrogenase B, 6-phosphogluconate dehydrogenase C, pentose-5-phosphate iso-merase D, pentose phosphate epimerase E, transaldolase F, transketolase G, phospho-hexoseisomerase. (Reproduced by permission from Williams JF. A critical examination of the evidence for the reactions of the pentose pathway in animal tissues. Trends Biochem Sri December 316, 1980.)...
Several heterofermentative LAB produce mannitol in large amounts, using fructose as an electron acceptor. Mannitol produced by heterofermentative bacteria is derived from the hexose phosphate pathway (Soetaert et al., 1999 Wisselink et al., 2002). The process makes use of the capability of the bacterium to utilize fructose as an alternative electron acceptor, thereby reducing it to mannitol with the enzyme mannitol dehydrogenase. In this process, the reducing equivalents are generated by conversion of one-third fructose to lactic acid and acetic acid. The enzyme reaction proceeds according to (theoretical) Equation 21.1 ... [Pg.397]

Glucose 6-phosphate dehydrogenase The enzyme that catalyzes the rate regulating step of the hexose monophosphate shunt, which produces NADPH required for inactivating oxygen radicals and thereby protects the RBC membrane from radical attack and rapture. [Pg.211]


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