Hexafluorine® solutions water washing

Improve the mechanical effect of water by attracting the chemicals and stopping their penetration through the skin. DIPHOTERINE and HEXAFLUORINE solutions are to chemicals what soap is to grease. They improve the washing effect and leave a cleaner surface. DIPHOTERINE solution is not only water but, to continue this picture, it is water plus soap. ... 

So, washing with water was a major improvement over non-washing. The use of DIPHOTERINE and HEXAFLUORINE solutions allows further treatment improvement over washing with water only. It therefore reduces the likelihood of injury due to chemical skin exposure. An amphoteric/chelating agent is able to stop or limit, as described in Chap. 3, the reactivity of chemicals such as acids, bases, oxidizers, reducers, chelating agents, and solvents. This property avoids or limits the skin lesions which result in chemical lesion injuries. 

HEXAIT.UORINE solution can provide the mechanical removal at the surface of the skin, as water does, and can avoid the wash-in effect due to its physical hyperosmolarity and restores pH toward neutral value because of its additional amphoteric properties, without any exothermic reaction. With its chelating properties, it will avoid fluoride ion diffusion into the skin. HEXAFLUORINE solution is nonirritant to the eye and the skin, nontoxic (oral LDso> 2,000 mg/kg in rats), and nonsensitizing [202]. 

With this model of human skin explant, after the validation of the experimental bum, the challenge was to compare various methods for washing HF bums. We selected two of them water washing followed by application of a 2.5 % calcium gluconate (CaG) cutaneous gel with topical application versus HEXAFLUORINE solution as a specific washing solution, which, due to its anti-acid and fluoride ion-chelating properties, matches the two dangers of HF corrosion and toxicity. 

The second part of this study was set with the same burned explants (30 pi 70 % HF for 20 s) to compare tap water washing for 15 min (volume around 2 L per explant) followed by superficial application of 2.5 % CaG and HEXAFLUORINE solution washing (400 mL during 10 min). 

Figure 4.66a, b show histological aspects at 24 h without any washing, compared to aspects after water washing and calcium gluconate (Fig. 4.67a, b) at the same time and HEXAFLUORINE solution (Fig. 4.68a, b). 

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