Heroin deaths caused

Potenza MN, Gold SJ, Roby-Shcmkowitz A, et al Effects of regulators of G protein-signaling proteins on the functional response of the mu-opioid receptor in a mel-anophore-based assay. J Pharmacol Exp Ther 291 482 91, 1999 Quaglio G, Talamini G, Lechi A, et al Study of 2708 heroin-related deaths in northeastern Italy 1985—98 to establish the main causes of death. Addiction 96 1127— 1137, 2001... 

Other effects caused by methamphetamine include headaches, decreased appetite, dry mouth, dilated pupils, trembling, chest pains, increased respiration and shortness of breath, hyperthermia (elevated body temperature), insomnia, and nausea and vomiting. In more severe cases (i.e., overdoses) it can produce seizures and convulsions, stroke, heart attacks, and death. The risk of encountering these more serious side effects are greatly increased when methamphetamine is used in combination with other drugs like cocaine, marijuana, alcohol, and heroin. 

Respiratory g and 5 ligands participate in the regulation of respiration (Su et al. 1998). Respiratory suppression is a regular feature of morphine, which suppresses all phases of respiration. Respiratory arrest is the most frequent cause of death from morphine or heroin overdose. In... 

With an ethos of drugs, sex, and rock n roll, the music industry has seen heroin claim many lives over the years. Heroin, specifically, has been the cause of many needless deaths of musicians both young and old, and of all types of music. Below are just of few of the lives taken by heroin. 

For more than 25 years, TCAs were one of the leading causes of drug-related deaths, exceeded only by alcohol-drug combinations and heroin (427). The risk of fatality resulting from a TCA overdose has severely limited their use now that newer, safer antidepressants are available. Nevertheless, overdoses of these medications still occur. There is still no simple antidote for a TCA overdose. A TCA overdose produces a characteristic clinical picture consisting of the following ... 

Many heroin users use heroin and alcohol together. There has been an evaluation of the pharmacokinetic interaction between heroin and alcohol and the role of that interaction in the cause of 39 heroin-related deaths that were attributed to either heroin or heroin + ethanol (69). The... 

Mirakbari SM. Heroin overdose as cause of death truth or myth. Aust J Forensic Sci 2004 36 73-8. 

An unbound morphine blood concentration of 100 ngl ml or more is considered potentially fatal. However, fatal cases of heroin intoxication occur in patients with blood morphine concentrations below 100 ng/ml. In 62 cases of heroin intoxication, death was associated with unbound morphine heart blood concentrations below 100 ng/ml in 21 cases and 100 ng/ml or over in 41 cases (51). In the 21 with low concentrations, respiratory tract infections occurred more often, and plausible causes of death were identified in 19. 

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