Heliotrope, Heliotropium

The Borage plant (syn. Forget-me-not) family (Boraginaceae Lindl.) contains L-ornithine (Figure 11 and 15) derived alkaloids, such as indicine-N-oxide in the heliotrope (Heliotropium indicum) and southern hound s tongue Cynoglosum creticum) species (Table 8). Farsam et al. reported on new alkaloids from... 

Heliotrope Heliotropium species Snake root Rauwolfia serpentina... 

In mammals, phenobarbital and phenytoin increase serum ceruloplasmin concentrations (Aaseth and Norseth 1986). Chronic copper poisoning in sheep is exacerbated when diets contain heliotrope plants (Heliotropium sp., Echium spp., Senecio sp.). Aggravated effects of the heliotrope plants include reduced survival and a twofold to threefold increase in liver and kidney copper concentrations when compared to control animals fed copper without heliotropes (Howell et al. 1991). Rats given acutely toxic doses of 2,3,7,8-tetrachlorodibenzo-para-dioxin had elevated concentrations of copper in liver and kidney because of impaired biliary excretion of copper (Elsenhans et al. 1991). Morphine increases copper concentrations in the central nervous system of rats, and dithiocarbam-ates inhibit biliary excretion (Aaseth and Norseth 1986). In human patients, urinary excretion of copper is increased after treatment with D-penicillamine, calcium disodium EDTA, or calcium trisodium diethylenetriamine penta acetic acid (Flora 1991). 

Symphytum officinale (black wort) Heliotropium species (heliotrope) Armoracia rusticana (horseradish) Brassica nigra (black mustard) Raphanus sativus var. niger (black radish)... 

Hedeoma pulegoides (pennyroyal) Heliotropium species (heliotrope) Hintonia latiflora (copalchi bark) Humulus lupulus (hop)... 

Bull, L. B., Culvenor, C. C., Keast, J. C., and Edgar, G. 1956. An Experimental Investigation of the Hepatotoxic and of Other Effects on Sheep of the Consumption of Heliotropium europaeum L. Heliotrope Poisoning of Sheep. Australian Journal of Agricultural Research 7 281-332. 

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