Heart malignancy

Nuclear medicine studies may reveal information that is primarily anatomic in nature, or indicate the function of an organ on a regional basis (Table 1). These studies may be intended to identify new disease, confirm or deny suspected disease, or foUow the progress of treatment or the course of disease. The diseases may be relatively benign or extremely serious and can range from widespread medical problems such as ischemic heart disease to rarities such as Legge-Perthe s disease and malignant pheochromocytoma (7). 

Malignant hypertension is a dangerous condition that develops rapidly and requires immediate medical attention. Fbtients with malignant hypertension experience organ damage as die result of hypertension. Target organs of hypertension include the heart, kidney, and eyes (retinopadiy). 

Warfarin is used cautiously in patients with fever, heart failure, diarrhea, malignancy, hypertension, renal or hepatic disease, psychoses, or depression. Women of childbearing age must use a reliable contraceptive to prevent pregnancy. 

Other current nonmalignant disease or disorder, for example, congestive heart failure or peptic ulcer, that may or may not be related to the malignant disease... 

The results were that income inequality was strongly associated with lack of social trust, and that states with high levels of social mistrust had higher age-adjusted rates of total mortality (level of social trust explained 18% of variance in total mortality, under their regression). Lower levels of social trust were associated with higher rates of most major causes of death, including coronary heart disease, malignant neoplasms, cerebrovascular disease, unintentional injury, and infant mortality. 

On the other hand, per capita group membership was strongly inversely correlated with all-cause mortality. Level of group membership was also a predictor of coronary heart disease, malignant neoplasms, and infant mortality. 

Comorbidities (chronic obstructive pulmonary disease, diabetes, renal or congestive heart failure, malignancy)... 

In humans, also, preferential sites exist for the formation of metastasis from various primary tumors [reviewed in Zetter (Zl)]. Thus, bone is a preferred site for metastasis from primary malignancies in breast, prostate, and kidney, while liver is a frequent metastatic site for tumors originating in the colon. Different types of leukemias vary widely in their ability to spread to liver, lymph, bone, and spleen. Some organs, however, are rarely colonized by metastatic growth. These resistant sites include skeletal muscle, heart, and skin. 

As the prevalence of obesity increases worldwide, so does the prevalence of associated co-morbidities type-2 diabetes, chronic obstructive sleep apnoea, cardiovascular disease (hyper-tension, coronary artery disease and congestive heart failure, stroke and peripheral vascular disease), fatty liver disease, various malignancies (Table 7.2), gallstones, subfertility, musculo-skeletal problems and depression. 

In a retrospective mortality study of over 900 workers exposed from 3 months to 23 years to median time-weighted acetone concentrations up to 1070 ppm there was no significant risk of death from any cause (all causes, malignant neoplasm, circulatory system disease, ischemic heart disease) compared with rates for the general population. ... 

Higgins SL, Hummel JD, Niazi IK, et al. Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias, [see comment]. J. Am. Coll. Cardiol. 2003 42 1454-9. 

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