Oral contraceptives headache with

These potential benefits are balanced by a slightly increased risk of gallbladder disease, hypertension, myocardial infarction, cerebral infarction, and pulmonary embolism. The increased risk of stroke and heart attack associated with the pill is accentuated when compounded by other risk factors, including smoking, migraine headaches, and advancing age. Indeed, convincing data support an upper age limit of 35 years for oral contraceptive use by women who smoke. 

Headache has long been reported as a reaction to oral contraceptives, just as it occurs unpredictably with many other forms of drug treatment it is probable that women... 

A systematic review of published data on the occurrence of headache with the more modest combination products now used has shown little indication that they have a clinically important effect on headache in most women (142). Headache that occurs during early cycles of oral contraceptive use tends to improve or disappear with continued use. No clear evidence supports the common clinical practice of switching from one oral contraceptive to another in the hope of attaining a lower incidence of headache. However, manipulating the extent or duration of estrogen withdrawal during the cycle may provide benefit. 

Doses of griseofulvin are 15-20 mg/kg/d for 6 to 8 weeks in children with the microsized form. More frequent side effects are minor headaches, gastrointestinal reactions and cutaneous eruptions. The major drug interactions have been noted with phenobarbital, anticoagulants and oral contraceptives. 

Other relative contraindications should be considered on an individual basis, including migraine headaches, hypertension, diabetes mellitus, obstructive jaundice of pregnancy or prior oral contraceptive use, and gallbladder disease. If elective surgery is planned, many physicians discontinue oral contraceptives for several weeks to minimize the possibility of thromboembolism. These agents should be used with care in women with prior gestational diabetes or uterine fibroids low-dose pills are preferred in such cases. 

Charles JA, Pullicino PM, Stoopack PM, Shroff Y. Ischemic colitis associated with nar-alriptan and oral contraceptive use. Headache (2005) 45, 386-9. 

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