Hand deposits persistence

In addition to the random nature of FDR deposition, the retention time is very low, disappearing rapidly from the hands, face, and head hair but remaining longer on the upper outer garment. The residues are chemically stable and their persistence obviously depends entirely on what happens to the clothing after the incident. If the clothing is left undisturbed, the FDR will remain indefinitely. If the clothing is worn after deposition, there will be a loss as a consequence of normal activity, namely, motion, transfer, wind, rain, and so forth. (This is less applicable to FDR inside pockets pocket interiors are our most fruitful area.)... 

Children absorb lead from the diet with greater efficiency than adults (WHO, 2000). After absorption and distribution in blood, where most lead is found in erythrocytes, it is initially distributed to soft tissues throughout the body. Subsequently, lead is deposited in the bone, where it eventual accumulates. The half-life of lead in blood and other soft tissues is 28-36 days. Lead that is deposited in physiologically inactive cortical bones may persist for decades without substantially influencing the concentrations of lead in blood and other tissues. On the other hand, lead that is accumulated early in life may be released later when bone resorption is increased, e.g., as result of calcium deficiency or osteoporosis. Lead that is deposited in physiologically active trabecular bones is in equilibrium with blood. The accumulation of high concentrations of lead in blood when exposure is reduced may be due to the ability of bones to store and release lead. 

DSM-IV-TR (American Psychiatric Association 2000) recognizes inhalant-, anesthetic-, and solvent-related disorders (Table 13-8). Anesthetics are associated with substance-induced anxiety disorder. Inhalant-related disorders include intoxication, delirium, persisting dementia, psychotic disorders with delusions or hallucinations, mood or anxiety disorders, and disorders not otherwise specified. Diagnosis depends on history or laboratory studies described earlier in this chapter. Physical signs such as deposits from inhalants around the mouth or nose or on hands and clothing may indicate recent use (Westermeyer 1987). Nasal membranes may be inflamed (Wester-meyer 1987). 

---