Guarea species

Trees native to the South American Andes. Part used is the dried bark. The original cocillana bark is believed to be derived from G. rusbyi. However, there is evidence that the current drug is obtained from other closely related Guarea species and is not the same as the cocillana first introduced into modem medicine (usd 23rd). The bark is collected in Haiti and Bolivia (evans). 

COCILLANA (Syn. Guarea, Guapi Bark) Guareae Cortex is the bark of Guarea rusbyi (Britt.), Rushy and closely related species, family Meliaceae. It is obtained mainly from Bolivia. Cocillana is a more stimulating expectorant than Ipecacuanha. The unidentified alkaloid fraction contributes most probably to the expectorant effect. 

Source Guarea rusbyi (Britt.) Rushy (syn. Sycocarpus rusbyi Britt.) and closely related species (Family Meliaceae). 

Many South American species and even genera remain uninvestigated, but since most of these are rather closely related to the Trichilia-Guarea group, it is likely that they will contain similar extractives. 

Bevan, C. W. L., J. W. Powell, and D. A. H. Taylor West African Timbers Part VI. Petroleum Extracts from Species of the Genera Khaya, Guarea, Carapa and Cedrela. J. Chem. Soc. 1963, 980. 

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