Guanine-DNA

Mattern J, Eichhorn U, Kaina B, Volm M (1998) 0 -Meth guanine-DNA methyl-transferase activity and sensitivity to cydophoshamide and dsplatin in human lung tumor xenografts. Int. ] Cancer 77 919-922... [Pg.81]

Removal of Alkyl Groups O6- Methyl Guanine DNA Methyltransferase Repair (MGMT)... [Pg.270]

S. Fujiwara, M. Takagi, T. Imanaka, Y. Kai, Crystallization and preliminary X-ray crystallographic analysis of archaeal 06-methyl-guanine-DNA methyltransferase, Acta Crys-tallogr. D Biol. Crystallogr. 1998, 54(2) Pt 6, 1395-1396. [Pg.92]

B., and Geadntov, N.E. (2007) Sequence context- and temperature-dependent nucleotide exdsion repair of a benzojo] pyrene diol epoxide-guanine DNA addud catalyzed by thermophilic UvrABC proteins. Biochemistry, 46, 7006-7015. [Pg.237]

Cai, Y., Patel, D.J., Geadntov, N.E., and Broyde, S. (2007) Dynamics of a benzojo] pyrene-derived guanine DNA lesion in TGT and CGC sequence contexts enhanced mobility in TGT explains conformational heterogeneity, flexible bending, and greater susceptibility to nucleotide exdsion repair./. Mol. Biol., 374, 292-305. [Pg.237]

B. F., and Harris, C.C. (1984) (/ -alkyl-guanine-DNA alkyltransferase activity in normal human tissues and cells. Cancer Res., 44, 2855-2857. [Pg.326]

Choi, J.Y., Angel, K.C., and Guengerich, F.P. (2006) Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase K. J. Biol. Chem., 281, 21062-21072. [Pg.328]

Choi, J.Y. and Guengerich, F.P. (2005) Adduct size limits efficient and error-free bypass across bulky N2-guanine DNA lesions by human DNA polymerase r. J. Mol. Biol., 352, 72-90. [Pg.328]

JV2-guanine DNA adducts by human DNA polymerase i. J. Biol. Chem., 281, 12315-12324. [Pg.328]

Russo N, Toscano M, Grand A, Jolibois F (1998) Protonation of thymine, cytosine, adenine, and guanine DNA nucleic acid bases theoretical investigation into the framework of density functional theory. J Comput Chem 19 989-1000. doi 10.1002/(SICI)1096-987X( 19980715)19 9<989 AID-JCC1 >3,0.CO 2-F... [Pg.179]

Harrington CF, Le Pla RC, Jones GDD, Thomas AL, Farmer PB. Determination of cisplatin 1,2-intrastrand guanine-guanine DNA adducts in human leukocytes by high-performance liquid chromatography coupled to inductively coupled plasma mass spectrometry. Chem Res Toxicol 2010 33 1313—21. [Pg.649]

Malayappan, B. et (2010) Quantitative high-performance liquid chromatography-electrospray ionization tandem mass spectrometry analysis of bis-N7-guanine DNA-DNA cross-links in white blood cells of cancer patients receiving cyclophosphamide therapy. Anal. Chem., 82 (9), 3650-3658. [Pg.223]

Deactivation Mechanism in Cytosine-Guanine DNA Base Pair. 1392... [Pg.1359]

Ludlum, D.B., Kent, S., Mehta, J.R., 1986. Formation of 06-ethylthioethylguanine in DNA by reaction with the sulfur mustard, chloroethyl sulfide, and its apparent lack of repair by 06-alkyl guanine-DNA alkyltransferase. Carcinogenesis 7, 1203-1206. [Pg.516]

Raman, R., Raguram, S., Venkataraman, G., Paulson, J.C., Sasisekharan, R., 2005. Glycomics an integrated systems approach to structure-function relationships of glycans. Nat. Methods 2,817-824. Rao, C., Tam, J.P., 1994. Synthesis of peptide dendrimer. J. Am. Chem. Soc. 16, 6975—6976. Rattanakiat, S., Nishikawa, M., Funabashi, H., Luo, D., Takakura, Y, 2009. The assembly of a short hnear natural cytosine-phosphate-guanine DNA into dendritic structures and its effect on immunostimulatory activity. Biomaterials 30 (29), 5701-5706. [Pg.42]

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