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Growth Sulfating factor

It is almost three decades since Salmon and Daughaday (S3) described a GH-dependent serum factor which could stimulate sulfate incorporation by cartilage in vitro, an activity apparently not inherent in GH itself. This sulfation factor was postulated to mediate the known effects of GH in vivo on skeletal growth. Subsequent studies revealed a range of GH-dependent activities in rat cartilage stimulation of sulfate and leucine uptake into glucosaminoglycans (S4), proline conversion to collagen hydroxyproline (D3), and incorporation of uridine into RNA and thymidine into DNA (Gl,... [Pg.55]

Yde, H., The growth hormone dependent sulfation factor in serum from patients with various types of diabetes. Acta Med. Scand. 186, 293-297 (1969). [Pg.115]

M Lyon, JA Deakin, H Rahmoune, DG Fernig, T Nakamura, JT Gallagher. Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate. J Biol Chem 273 271-278, 1998. [Pg.308]

It was observed that for CCK and related peptides sulfation of the tyrosine residue is essential for triggering the full hormonal response.131 32 More recently, additional sulfated peptides have been identified as CCK-58, 135 phytosulfokinine-a, as peptide growth factor in plants 136 as well as various toxins from Conus venom. 137138 This observation has fostered intensive research to develop synthetic methods for efficient production of tyrosine O-sulfated peptides by chemical and enzymatic approaches. [Pg.426]

Takiyama (6) prepared highly monodispersed spindle-type particles of barium sulfate (BaS04) by decomposing the Ba-EDTA complex with hydrogen peroxide. In this reaction, the initial concentration of the Ba-EDTA complex is a decisive factor in separation of nucleation and growth stages. [Pg.328]

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Sulfation factor

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