Group B Streptococci

The treatment of bacterial infections of the central nervous system highlights a number of important therapeutic considerations. Bacterial meningitis is caused by a variety of bacteria although their incidence varies with age. In the neonate, E. coli and group B streptococci account for the majority of infections, while in the preschool child H. influenzae is the commonest pathogen. Neisseria meningitidis has a... 

Hematogenous Neonates Prepubertal children Long bones (femur, tibia) Long bones (femur, tibia) Staphylococcus aureus,3 E. coli, group B streptococci 5. aureus Nafcillin and cefotaxime Nafcillin or cefazolin... 

Enteric gram-negative bacilli, anaerobes, group B streptococci, and enterococci are all possible pathogens that may... 

Stringer, J. Development of a phage-typing system for group-B streptococci. J. Med. Microbiol. 1980,13,133-143. 

Hysterectomy Enteric gram-negative bacilli, anaerobes, group B streptococci, enterococci Vaginal Cefazolin 1 g x l Abdominal Cefotetan 1 g x 1 or cefazolin 1 g x 1 Metronidazole 1 g IV x 1 is recommended alternative for penicillin allergy IA... 

A special example of cell-cell interaction is the adherence of group B streptococci to canine, epithelial cells that are infected with influenza A virus. However, this capacity was blocked in the presence of tunicamycin, and this result supports the concept that adherence of streptococci to mammalian cells involves recognition of viral hemagglutinin, or its carbohydrate complement, the synthesis of which is blocked by tunicamycin.556... 

Hysterectomy Enteric gram-negative rods, anaerobes, enterococci, group B streptococci Cefazolin... 

Several variations of this concept have been reported.50-52 For example, Ley and Priepke50 prepared the trisaccharide unit, which is derived from the common polysaccharide antigen of a group B Streptococci by a facile one-pot two-step synthesis (Scheme 4.18). In this... 

Cholera toxin Group B streptococci High levels of IgA in cervicovaginal secretions 229... 

Hordness, K., Tynning, T., Brown, T. A., Haneberg, B., and Jonsson, R. (1997), Nasal immunization with group B streptococci can induce high levels of specific IgA antibodies in cervicovaginal secretions of mice, Vaccine, 15,1244-1251. 

A facile one-pot synthesis of a trisaccharide unit from the 51. common polysaccharide antigen of group B Streptococci using cyclohexane-1,2-diacetal (CDA) protected rhamnosides. Angew. 

For Escherichia coli give cefotaxime or ceftazidime perhaps with gentamicin. For Group B streptococci give benzylpenicillin plus gentamicin. Consult a specialist text for details of doses for neonates. 

Endophthalmitis occurred in a patient from Singapore (93). Group B streptococci were isolated from the blood. Despite aggressive intravitreal antibiotic therapy the affected eye lost its light perception. 

Increased antenatal administration of ampicillin for the prevention of neonatal group B streptococcal disease may be responsible for the higher incidence of more severe neonatal sepsis with ampicillin-resistant non-group B streptococci, without a change in the overall infection rate (203,204). 

Vallejo JG, Baker CJ, Edwards MS. Interleukin-6 production by human neonatal monocytes stimulated by type III group B streptococci. J Infect Dis 1996 174 332-7. 

Bergeron MG, Ke D, Menard C, Picard FJ, Gagnon M, Bernier M, et al. Rapid detection of group B streptococci in pregnant women at delivery. N Engl JMed 2000 343 175-9. 

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