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Ground squirrel hepatitis

Ara-A-5 -monophosphate [29984-33-6] (ara-AMP), C2QH24N OyP, is more water-soluble than ara-A, and therefore can be used in higher dosage during the first hours of treatment of viral infections. Ara-AMP has been shown to decrease virion-associated DNA polymerase concentrations in ground squirrels carrying ground squirrel hepatitis vims. The hypoxanthine derivative, ara-HxMP [54656-49-4] (24) is more water-soluble, appears to have a similar antiviral spectmm to ara-A, and is considerably less toxic (48). [Pg.307]

Hepatitis B virus (HBV) (125) belongs to hepadnavirus family of DNA-containing viruses that also include woodchuck hepatitis virus (126), ground squirrel hepatitis virus (127), duck hepatitis B virus (128), and heron hepatitis B virus (129). These viruses replicate primarily in the liver cells, and establish chronic infection in their respective hosts. In humans, primary... [Pg.527]

See other pages where Ground squirrel hepatitis is mentioned: [Pg.423]    [Pg.904]    [Pg.307]    [Pg.423]    [Pg.904]    [Pg.307]    [Pg.250]   
See also in sourсe #XX -- [ Pg.423 ]



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