Green perspective

From a green perspective, decreased yields, by-product formation and inability to reproduce key product properties will invariably increase waste and require greater materials and energy use. Longer cycle times invariably will lead to increased energy use and in some cases, increased materials use. 

Before we begin to discuss this, however, we need to think about a few important points as we attempt to apply a green perspective to metrics and cost. First, most people do not really consider what lies behind the goods and services that we extract from the environment for free. For example, we do not pay significantly for the air... 

The replacement of relatively harmful volatile organic solvents with, alternative, less environmentally damaging solvent systems/approaches is generating interest from a green perspective for synthetic chemistry and catalysis. A number of these are reviewed elsewhere in this compilation. Here, we highlight some notable developments in green applications of water, supercritical (sc) fluids, ionic liquids, and fluorous solvents in organometallic chemistry. 

Ionic liquids offer a number of potential advantages over organic solvents from a green perspective. Loss of solvent by evaporation is effectively zero. Reactions may be more selective in an ionic liquid, thereby reducing separation costs both from an economic and environmental perspective. For catalytic reactions as well as increasing selectivity, an ionic liquid may stabilize a catalyst and so increase lifetime and turnover number. The use of ionic liquids in catalysis has been the subject of several reviews in recent years,and organometallic chemistry in ionic liquids is reviewed in Volume 1. 

The Biginelli reaction A green perspective 12COC507. Dihydropyrimidines (synthesis, tautomerism, reactivity, skeleton types, including mono-, hi-, tri-, tetracyclic, bicyclo-, and spirocompounds, and biological activities) 13H(87)1441. 

Panda, S. S., Khanna, R, Khanna, L. (2012). Biginelli reaction a green perspective. Current Organic Chemistry, 16, 507-520. 

Resume Criteria for an Active Fluorinated Chromia Catalyst 203 Catalytic Fluorination Leading to Hydrofluoroolefins 204 Production of Chloromethane A Green Perspective 205... 

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