GRAS foods

Health and Safety. The FDA affirmed (R-R, R -tartaric acid as a generally-recognized-as-safe (GRAS) food substance (88). 

Recommendations for submission of chemical and technological data for direct food additive and GRAS food ingredient petitions, 1993 (http //vm.cfsan.fda.gov/ dms/opa-cg4.html)... 

The parent CDs as GRAS food additives are suitable for oral pharmaceutical use when used at the levels approved for foods. The GRAS estimated daily mean oral exposures for P-CD, a-CD, and y-CD were reported as 300, 1700, and 4000mg/day, respectively. These levels provide reasonable quantities for consideration in oral pharmaceutical products. As stated earlier, the parent CDs, however, are not suited for intravenous (TV) use due to the early reports of their renal toxicity, and this limitation led researchers to introduce chemical modifications to provide new, system-ically safe CDs for use in parenteral pharmaceuticals. 

Recommendations for Submission of Chemical and Technological Data for Direct Food Additive and GRAS Food Ingredient Petitions. Office of Premarket Approval. U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition, May 1993. 

Ennen, S., Trehalose gets GRAS, Food Processing, August, 44 (2001). 

Table 11.2 Organic Acids Included in the FDA s List of GRAS Food Additives...

No safety concerns about the use of cinnamaldehyde as an herbal remedy, food additive, or pesticide has been expressed. The U.S. Food and Drug Administration (FDA) has classified the compound as a generally-recognized as safe (GRAS) food additive, permitting its continued use as a food additive in the United States. 

Scientific Literature Reviews on Generally Recognized as Safe (GRAS) Food Ingredients - Silicates, Tracor-Jitco,... 

United States Federal Food, Drug, and Cosmetic Act (21 U.S.C. 301) Food Additive (21 C.F.R. 170, 171, and 172) GRAS (21 C.F.R. 182, 184, and 186) Food additive. Substances Generally Recognized as Safe (GRAS) Food Additive GRAS... 

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