Gram-positive/negative bacteria tetracyclines

Tetracyclines are the first broad-spectrum antibiotic used to impede the growth of gram-positive and -negative bacteria. Tetracyclines are prescribed for acne vulgaris, actinomycosis, anthrax, bronchitis, and urinary tract infections. Demeclocycline, a member of the tetracycline family, is also prescribed for syndrome of inappropriate antidiuretic hormone (SIADH). Demeclocycline inhibits water-induced reabsorption in the kidneys. 

Erythromycin is active against gram-positive and certain gram-negative bacteria, also against Rickettsia and spirochaetes. It is used for patients who are allergic to or do not respond to treatment with penicillins or tetracyclines. 

Tetracyclines are broad-spectrum antibiotics. effective against Gram-positive and Gram-negative bacteria, also against Rickettsiae (typhus fever) and certain other organisms. 

Tetracyclines. The tetracycliaes are a small group of antibiotics characterized as containing a polyhydronaphthacene nucleus. Commercially the tetracyclines are very important. They have been used clinically against gram-positive and gram-negative bacteria, spirochete, mycoplasmas, and rickettsiae... 

Tetracyclines are broad-spectrum antibiotics with activity against Gram-positive and Gram-negative bacteria that have been widely used for the treatment of infectious diseases in veterinary and human medicine, as well as additives in animal foodstuffs. Normally tetracyclines are not found at high levels in the environment because they readily precipitate with cations such as calcium and are accumulated in sewage sludge or sediments [3,20,26]. 

Both antibiotic-specific and MDR pumps are known to confer clinically relevant resistance [22, 53]. The former are carried on plasmids and transposons. While they can be rapidly spread between various strains, they are at hand only in a proportion of a total population of a given species. Tet and Mef pumps, which confer resistance to tetracycline and macrolides, respectively, in both Gram-positive and Gram-negative bacteria, are clinically important and highly prevalent antibiotic-specific transporters. 

Tetracyclines, which are bacteriostatic, have the broadest spectrum of activity and are effective against infections with Gram-positive and Gram-negative bacteria Rickettsia, Mycoplasma, amoeba, and Chlamydia. These agents consist of ... 

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