Graft-versus-host disease diagnosis

Filipovich AH, Weisdorf D, Pavletic S, et al. National Institutes of Health Consensus Development Project on criteria for clinical trials in chronic graft-versus-host disease I. Diagnosis and staging working group report. Biol Blood Marrow Transplant 2005 11 945-956. 

Differential diagnosis of graft-versus-host disease currently depends on organ biopsy to distinguish it from other common complications associated with transplantation. As a means of avoiding repeated biopsies, one group analyzed the urine of patients after hematopoietic stem cell transplantation... 

Aztreonam was the suspected cause of toxic epidermal necrolysis in two patients undergoing bone marrow transplantations (11). Graft-versus-host disease seemed a less likely diagnosis of the cutaneous manifestations. 

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