Gonal

Stmcture tetra- gonal hexa- gonal ortho- rhombic tetra- gonal ortho- rhombic... 

Fig. 1.4 Phase encoding scheme in three ween the rf pulses and before the acquisition of dimensions. Three pulsed gradients in ortho- the echo signal. In practice, the gradients are gonal directions are applied and are varied often applied simultaneously. The indices 1, 2 independently of each other (symbolized by the and 3 represent orthogonal directions with no diagonal line). The actual timing of the gradi- priority being given to a particular choice of ents is arbitrary provided they are placed bet- combinations.

Fig. 1.11 Typical basic three-dimensional negative intensity directly before the actual imaging sequence with slice selection, frequen- read gradient. The shape of the 180° rf pulse cy encoding and phase encoding in three ortho- is drawn schematically to indicate that a soft gonal directions. The compensating lobe for pulse is used, the read gradient is drawn as a rectangle with...

Gonal-F Human follicle-stimulating hormone Serono laboratories Female infertility... 

Hormones Gonal F, Luveris, Ovitrelle/Ovidrel, Puregon/ Follistim, Thyrogen... 

Follicle stimulating hormones Infertihty Gonal-f, Puregon... 

The first studies of dendrimer-encapsulated metal nanoparticles focused on Cu [82]. This is because Cu + complexes with PAMAM and PPI dendrimers are very well behaved and have easily interpretable UV-vis and EPR spectra. For example, Fig. 4a shows absorption spectra for Cu + coordinated to different ligands. In the absence of dendrimer and in aqueous solutions Cu + exists primarily as [Cu(H20)g] +, which gives rise to a broad, weak absorption band centered at 810 nm. This corresponds to the well-known d-d transition for Cu in a tetra-gonally distorted octahedral or square-planar ligand field. 

Chan, G.K.L., Van Voorhis, T. Density-matrix renormalization-group algorithms with nonortho-gonal orbitals and non-Hermitian operators, and applications to polyenes. J. Chem. Phys. 2005, 122(20), 204101. 

Fig. 2.11 Structure of hematite, a) Hexagonal lined, c) Arrangement of octahedra. Note their close packing of oxygens with cations distributed face-sharing, d) Ball-and-stick model. Unit cell in the octahedral interstices. Unit cell outlined. outlined, e) 03-Fe-03-Fe-03 triplets, (a, b Eggle-b) View down the c-axis showing the distribution ton et al., 1988 with permission c, d Stanjek, of Fe ions over a given oxygen layer and the hexa- unpubl. e Stanjek, 1991 with permission) gonal arrangement of octahedra. Unit cell out-...

Dosage form Gonal-F is a sterile, lyophilized powder intended for subcutaneous injection after reconstitution with sterile water for injection. Each ampule contains recombinant FSH 37.5 lU, 75 lU, or 150lU. 

Route of administration Gonal-F is to be administered as a subcutaneous injection. 

Pharmacokinetics The absorption rate of Gonal-F following subcutaneous or intramuscular administration was found to be slower than the elimination rate. Hence the pharmacokinetics of Gonal-F are absorption rate-limited. After intravenous administration to pituitary down-regulated, healthy female volunteers, the serum profile of FSH appears to be described by a two-compartment open model with a distribution half-life of about 2 to 2.5 hours. Steady-state serum levels were reached after 4 to 5 days of daily administration. 

Disposition FSH metabolism following administration of Gonal-F has not been studied in humans. FSH renal clearance was 0.07 liter/h after intravenous administration representing approximately 1/8 of total clearance. 

Microcrystals exhibit properties distinctly different from those of bulk solids. The fractional change in lattice spacing has been found to increase with decreasing particle size in FejOj. Magnetic hyperfine fields in a-FejOj and FejO are lower in the microcrystalline phase compared to those of the bulk crystalline phases. The tetra-gonality (i.e. the departure of the axial ratio from unity) of ferroelectric BaTiOj decreases with decrease in particle size in PZT, the low-frequency dielectric constant decreases and the Curie temperature increases with decreasing particle size. The small particle size in microcrystals cannot apparently sustain low-frequency lattice vibrations. 

Parenteral powder to reconstitute 500, 1000, 2000 IU/mL for IM injection Follitropin alfa [rFSH] (Gonal-f)... 

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