Gonadotropin synthesis

Morphologically, this is demonstrated by the development of a multinuclear syncytium with apical microvilli [49], while functional differentiation is associated with induction and synthesis of hormones, such as human chorionic gonadotropin (hCG) and human placental lactogen (hPL) [50, 51]. Cultures of primary cytotrophoblasts have been used to study functional expression of P-gp, amino acid uptake, and hormonal stimulation of amino acid uptake and... 

While these steroids directly regulate sexual function, their synthesis and release are, in turn, controlled by gonadotropins — polypeptide hormones produced by the pituitary gland. The biology and medical applications of the gonadotropins are outlined in Chapter 8. Sex hormones produced naturally may be classified into one of three groups ... 

Fish Stimulate the release of gonadotropin, which in turn stimulates the synthesis of sex steroids, controlling oogenesis and vitellogenesis. Brooks et al. (2005)... 

Mechanism of Action A testosterone derivative that suppresses the pituitary-ovarian axis by inhibiting the output of pituitary gonadotropins. Causes atrophy of both normal and ectopic endometrial tissue in endometriosis. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are depressed in fibrocystic breast disease. Inhibits steroid synthesis and binding of steroids to their receptors in breast tissues. Increases serum levels of esterase inhibitor. Therapeutic Effect Produces anovulation and amenorrhea, reduces the production of est rogen, corrects biochemical deficiency as seen in hereditary angioedema. 

Therefore, both pituitary gonadotropins are required for optimal androgen function. LH acts on the Leydig cells to stimulate testosterone synthesis,... 

Hormones are proteins responsible for regulating molecular synthesis in vivo. The most well known therapeutic hormones are insulin, glucagon, growth hormones, and gonadotropins. 

PURPOSE AND RATIONALE Anterior pituitaries may be incubated directly, kept in culture or used for cell lines (Mittler and Meites 1964, 1966 Mittler et al. 1970 Sandow et al. 1972) in order to study the synthesis and release of gonadotropins in response to LH-RH. 

Group 3 indirect effects caused by the secretion of hypothalamic hormones, which in turn stimulate synthesis and secretion of gonadotropins. 

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