Gold sulfoxide complexes

Toste has reported the cyclization/rearrangement of aryl y-alkynyl sulfoxides catalyzed by a gold(I) N-heterocyclic carbene complex [90]. For example, treatment of phenyl 3-butynyl sulfoxide 52 with a catalytic 1 1 mixture of (IMes)Aud [IMes = l,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene] and AgSbFg led to isolation of... 

Key words Amino acids. Catalytic oxidation under ambient conditions, 2-chloroethyl ethyl sulfide, Co-catalysis by copper. Decontamination, Effect of ligands, Gold complexes. Mustard gas, Perfluorinated solvents. Solvent effect. Sulfoxide, Thioether... 

Catalysis for selective aerobic oxidation under ambient conditions. Thioether sulfoxidation catalyzed by gold complexes 227... 

Yuan and coworkers reported the use of HAUCI4 H2O as catalyst for the oxidation of sulfides to sulfoxides by hydrogen peroxide (Scheme 16.37). The corresponding sulfoxides were selectively obtained in the reaction and only small amounts of sulfones were observed in some of the reactions. Different functional groups were tolerated. The authors were able to reuse the gold complex up to six times without significant loss of activity. The reaction performs under mild conditions, in methanol at 25 °C and hydrogen peroxide was used as the oxidant. 

N. Farrell Chemical and Biological Activity of Metal Complexes Containing Dimethyl Sulfoxide (Platinum, Gold and Other Metal Chemotherapeutic Agents, ACS Symposium Series v. 209, Ed. S. J. Lippard) p. 279. ACS, Washington (1983). 

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