Gold nanoshells

When using nanoshells tuned to an absorbance at 820 nm, Hirsch et al. achieved the photothermal ablation of cultivated tumor cells by irradiation using near-IR laser light at 820nm in vitro [25]. When this system was applied to in vivo tumor therapy, the laser light irradiation of solid tumors inoculated in mice treated with the nanosheUs caused an increase in the temperature of the irradiation site, although a minimal increase was detected in the absence of nanoshell treatment. [Pg.283]

In addition, irreversible tissue damage was observed at the site treated with the nanoshells and laser-irradiated [25]. The same group also reported a photothermal therapeutic effect on solid tumors in mice when they injected PEG-modified gold [Pg.283]

Oldenburg, S.J., Jackson, J.B., Westcott, S.L. and Halas, N.J. (1999) Infrared extinction properties of gold nanoshells. Applied Physics Letters, 75, 2897-2899. [Pg.346]

F. and Buuren, T.v. (2005) Comment on Gold nanoshells improve single nanoparticle molecular sensors . Nano Letters, 5, 809-810. [Pg.347]

Pham T., Jackson J.B., Halas N.J., Lee T.R., Preparation and characterization of gold nanoshells coated with self-assembled monolayers, Langmuir 2002 18 4915-4920. [Pg.256]

Hirsch LR, Jackson JB, Lee A, Halas NJ, West J (2003) A whole blood immunoassay using gold nanoshells. Anal Chem 75 2377-2381... [Pg.225]

Wu G, Mikhailovsky A, Khant HA et al (2008) Remotely triggered liposome release by near-infrared light absorption via hollow gold nanoshells. J Am Chem Soc 130 8175-8177... [Pg.160]

Gold nanoshells [31] Imaging agent, thermal ablation... [Pg.1294]

Rasch MR, Sokolov KV, Korgel BA (2009) Limitations on the optical tunability of small diameter gold nanoshells. Langmuir 25(19) 11777-11785... [Pg.73]

Nehl CL, Grady NK, Goodrich GP, Tam F, Halas NJ, Hafner JH (2004) Scattering spectra of single gold nanoshells. Nano Lett 4(12) 2355-2359... [Pg.73]

Prodan E, Nordlander P, Halas NJ (2003) Electronic structure and optical properties of gold nanoshells. Nano Lett 3 1411-1415... [Pg.73]

Preston TC, Signorell R (2009) Growth and optical properties of gold nanoshells prior to the formation of a continuous metallic layer. ACS Nano 3(ll) 3696-3706... [Pg.73]

Qiana W, Tana Y, Dinga S, Wanga Y (2008) A label-free biosensor based on gold nanoshell monolayers for monitoring biomolecular interactions in diluted whole blood. Biosens Bioelectron 23(7) 1166-1170... [Pg.73]

As described in papers using gold nanoshells that have also shown surface plasmon bands in the near-1R region [36, 37], the targeted delivery of nanoparticles allows us to... [Pg.393]

A whole blood immunoassay using gold nanoshells. Anal. Chem., 75, 2377-2381. [Pg.403]

Gold nanoshells Tissue imaging, thermal abladve cancer therapy 43, 44... [Pg.458]

Gold Nanoshells, which are actually a gold shell surrounding a semiconductor that can be irradiated when reaching their target. This heats the nanoshell, which in turn kills the cancer cells. [Pg.33]

Gold is a metal that continues to be precious in the market place, in exploration, in medicine and in science and technology (1). Its unique chemical properties ensure that it continues to be researched and applied in many established and in many new fields, including the treatment of arthritis (2), as advanced biocompatible materials in medicine (3,4) in the nanoengineering of optical properties as gold nanoshells (5) and in biosensing (6). [Pg.68]

One of the most well-known applications is the use of gold nanoshells with localized heating for the targeted destruction of malignant cancer cells, an approach that involves minimal side effects (Lane and Kalil, 2005). [Pg.454]

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